Evidence mapPaperPMID 35853530Full record

ArticleDiabetes research and clinical practice2022

How introduction of automated insulin delivery systems may influence psychosocial outcomes in adults with type 1 diabetes: Findings from the first investigation with the Omnipod® 5 System.

William H Polonsky, Korey K Hood, Carol J Levy, Sarah A MacLeish, Irl B Hirsch, Sue A Brown, Bruce W Bode, Anders L Carlson, Viral N Shah, Ruth S Weinstock and 11 more

2 registry-linked trialsAbstract readMulticenter Study
In one paragraph

Article in Diabetes research and clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04196140 nacompletednot on this map

Evaluating the Safety and Effectiveness of the Omnipod Horizon™ Automated Glucose Control System in Patients With Type 1 Diabetes

TypeinterventionalSponsorInsulet CorporationRan2019 to 2022Enrolled240ConditionsType 1 Diabetes MellitusArmsOmnipod Horizon™ Automated Glucose Control System
NCT07348432 recruitingnot on this mapstarted 2024, after this paper: background citation

The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes

TypeobservationalSponsorMcGill UniversityRan2024 to 2026Enrolled106ConditionsInsulin Dependent Diabetes Mellitus, Feeding and Eating Disorders, Eating Behavior, Type 1 DiabetesArmsAutomated Insulin Delivery (AID) Systems, Carbohydrate Counting Inaccuracy Percentage
3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Transitioning to Omnipod 5Biomedicines · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Observational
  11. Assessing the iLet Bionic Pancreas Deployed in Primary Care and via Telehealth: A Randomized Clinical Trial.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. The Artificial Pancreas and Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

William H PolonskyBehavioral Diabetes Institute, 5230 Carrol Canyon Road Ste 208, San Diego, CA 92121, United States; University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States.
Korey K HoodDepartment of Pediatrics, Psychiatry & Behavioral Sciences, Stanford Diabetes Research Center, Stanford University School of Medicine, 279 Campus Drive, B300, Stanford, CA 94305, United States.
Carol J LevyIcahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, United States.
Sarah A MacLeishUniversity Hospitals Cleveland Medical Center, Rainbow Babies and Children's Hospital, 11100 Euclid Ave, Cleveland, OH 44106, United States.
Irl B HirschDepartment of Medicine, University of Washington, 750 Republican Street, Building F, Floor 3, Seattle, WA 98109, United States.
Sue A BrownDivision of Endocrinology, Center for Diabetes Technology, University of Virginia, 560 Ray C Hunt Dr, Charlottesville, VA 22903, United States.
Bruce W BodeAtlanta Diabetes Associates, 1800 Howell Mill Rd #450, Atlanta, GA 30318, United States.
Anders L CarlsonInternational Diabetes Center, Park Nicollet, HealthPartners, 3800 Park Nicollet Blvd, Minneapolis, MN 55415, United States.
Viral N ShahBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct #A140, Aurora, CO 80045, United States.
Ruth S WeinstockDepartment of Medicine, SUNY Upstate Medical University, 750 E Adams St, Syracuse, NY 13210, United States.
Anuj BhargavaIowa Diabetes Research, 1031 Office Park Rd Suite #2, West Des Moines, IA 50265, United States.
Thomas C JonesDepartment of Research, East Coast Institute for Research at The Jones Center, 265 Sheraton Blvd, Macon, GA 31210, United States.
Grazia AleppoFeinberg School of Medicine, Northwestern University, 645 N Michigan Ave Ste 530, Chicago, IL 60611, United States.
Sanjeev N MehtaJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA 02215, United States.
Lori M LaffelJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA 02215, United States.
Gregory P ForlenzaBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct #A140, Aurora, CO 80045, United States.
Jennifer L SherrDepartment of Pediatrics, Yale School of Medicine, 333 Cedar St, New Haven, CT 06510, United States.
Lauren M HuyettInsulet Corporation, 100 Nagog Park, Acton, MA 01720, United States.
Todd E VienneauInsulet Corporation, 100 Nagog Park, Acton, MA 01720, United States.
Trang T LyInsulet Corporation, 100 Nagog Park, Acton, MA 01720, United States. Electronic address: tly@insulet.com.
Omnipod 5 Research Group

Funding

PILOT STUDY--SECRETORY TARGETING IN PANCREATIC B CELLSP30DK036836 · JOSLIN DIABETES CENTER · 1986 to 2025
$12.1M
NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

aimsTo evaluate psychosocial outcomes for adults with type 1 diabetes (T1D) using the tubeless Omnipod® 5 Automated Insulin Delivery (AID) System.

methodsA single-arm, multicenter (across the United States), prospective safety and efficacy study of the tubeless AID system included 115 adults with T1D. Participants aged 18-70 years completed questionnaires assessing psychosocial outcomes - diabetes distress (T1-DDS), hypoglycemic confidence (HCS), well-being (WHO-5), sleep quality (PSQI), insulin delivery satisfaction (IDSS), diabetes treatment satisfaction (DTSQ), and system usability (SUS) - before and after 3 months of AID use. Associations among participant characteristics, psychosocial measures and glycemic outcomes were evaluated using linear regression analyses.

resultsAdults using the tubeless AID system demonstrated improvements in diabetes-specific psychosocial measures, including diabetes distress, hypoglycemic confidence, insulin delivery satisfaction, diabetes treatment satisfaction, and system usability after 3 months (all P < 0.001). No changes in general well-being or sleep quality were observed. The psychosocial outcomes assessed were not consistently associated with baseline participant characteristics (i.e., age, sex, diabetes duration, glycemic outcomes including percent time in range 70-180 mg/dL, percent time below range < 70 mg/dL, hemoglobin A1c, or insulin regimen).

conclusionsUse of the Omnipod 5 AID system was associated with significant improvements in diabetes-related psychosocial outcomes for adults with T1D. CLINICAL TRIALS REGISTRATION NUMBER: NCT04196140.

Indexed as

Diabetes Mellitus, Type 1AdultBlood GlucoseBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsInsulin, Regular, HumanProspective StudiesBlood GlucoseHypoglycemic AgentsInsulinInsulin, Regular, HumanAutomated insulin deliveryClosed-loop systemPsychosocial outcomesType 1 diabetes

Identifiers

PMID35853530
PMCPMC10901155

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.