Evidence map›Paper›PMID 35865706›Full record

ReviewFrontiers in pediatrics2022

The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia.

Oluyinka O Olutoye Ii, Walker D Short, Jamie Gilley, J D Hammond Ii, Michael A Belfort, Timothy C Lee, Alice King, Jimmy Espinoza, Luc Joyeux, Krithika Lingappan and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Oluyinka O Olutoye IiDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Walker D ShortDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Jamie GilleyDivision of Neonatology, Department of Pediatrics, Texas Children's Hospital, Houston, TX, United States.
J D Hammond IiDivision of Neonatology, Department of Pediatrics, Texas Children's Hospital, Houston, TX, United States.
Michael A BelfortTexas Children's Fetal Center, Baylor College of Medicine, Houston, TX, United States.
Timothy C LeeDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Alice KingDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Jimmy EspinozaTexas Children's Fetal Center, Baylor College of Medicine, Houston, TX, United States.
Luc JoyeuxDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Krithika LingappanDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Jason P GleghornDepartment of Biomedical Engineering, University of Delaware, Newark, DE, United States.
Sundeep G KeswaniDivision of Pediatric Surgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States.
Texas Children's Hospital · USBaylor College of Medicine · USChildren's Hospital of Philadelphia · USUniversity of Delaware · US

Funding

Research Training Program in Cardiovascular SurgeryT32HL139430 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Todd K Rosengart · 2018 to 2026
$2.9M
NHLBI NIH HHS T32 HL139430
6 · The paper itself

Abstract

Congenital diaphragmatic hernia (CDH) is a complex disease associated with pulmonary hypoplasia and pulmonary hypertension. Great strides have been made in our ability to care for CDH patients, specifically in the prenatal improvement of lung volume and morphology with fetoscopic endoluminal tracheal occlusion (FETO). While the anatomic effects of FETO have been described in-depth, the changes it induces at the cellular and molecular level remain a budding area of CDH research. This review will delve into the cellular and molecular effects of FETO in the developing lung, emphasize areas in which further research may improve our understanding of CDH, and highlight opportunities to optimize the FETO procedure for improved postnatal outcomes.

Indexed as

cellular and molecular factorscongenital diaphragmatic hernia (CDH)FETOpulmonary developmentpulmonary hypertensionpulmonary hypoplasiatracheal occlusion (TO)

Identifiers

PMID35865706
PMCPMC9294219
OpenAlexW4283818695

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.