Evidence map›Paper›PMID 35868118›Full record

ArticleJournal of molecular graphics & modelling2022

Elucidating the binding mechanism of LPA species and analogs in an LPA

Huiqun Wang, Mengchu Li, Celsey M St Onge, Babette Fuss, Yan Zhang

Abstract read
In one paragraph

Article in Journal of molecular graphics & modelling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huiqun WangDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, United States.
Mengchu LiDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, United States.
Celsey M St OngeDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, United States.
Babette FussDepartment of Anatomy and Neurobiology, Virginia Commonwealth University Medical Center, Richmond, VA, 23298, United States.
Yan ZhangDepartment of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, United States. Electronic address: yzhang2@vcu.edu.
Virginia Commonwealth University · USVirginia Commonwealth University Medical Center · US

Funding

Mu Opioid Receptor Modulator Development to Treat Opioid Use DisorderUH3DA050311 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ZHANG, YAN · 2023 to 2025
$4.3M
Non-peptide Mu Opioid Receptor Selective AntagonistsR01DA024022 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ZHANG, YAN · 2009 to 2019
$3.5M
Novel fentanyl derivatives as counteracting agents against fentanylUG3DA050311 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ZHANG, YAN · 2019 to 2020
$2.2M
Development of a Potential Treatment for Polysubstance Use DisordersF31DA054796 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ST. ONGE, CELSEY MACKENNA · 2021 to 2022
$80k
NIDA NIH HHS F31 DA054796NIDA NIH HHS R01 DA024022NIDA NIH HHS UG3 DA050311NIDA NIH HHS UH3 DA050311
6 · The paper itself

Abstract

Lysophosphatidic acid receptor 4 (LPA

Indexed as

LysophospholipidsReceptors, Lysophosphatidic AcidLigandsLigandsLysophospholipidsReceptors, Lysophosphatidic AcidLPA speciesLysophosphatidic acid receptor 4 (LPA(4))Structure activity relationship via modeling

Identifiers

PMID35868118
PMCPMC13276977
OpenAlexW4285602695

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.