Evidence map›Paper›PMID 35869379›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

Safety and long-term efficacy of cryoballoon ablation for atrial fibrillation in octogenarians: a multicenter experience.

Federico Cecchini, Giacomo Mugnai, Saverio Iacopino, Juan Pablo Abugattas, Bert Adriaenssens, Maysam Al-Housari, Alexandre Almorad, Gezim Bala, Antonio Bisignani, Carlo de Asmundis and 10 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  3. Article
  4. Response to Letter to the Editor.Clinical cardiology · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Federico Cecchini *Electrophysiology Unit, Maria Cecilia Hospital, Via Corriera, 1, 48033, Cotignola, RA, Italy. cecchinifederico1989@gmail.com.
Giacomo Mugnai *Heart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Saverio IacopinoElectrophysiology Unit, Maria Cecilia Hospital, Via Corriera, 1, 48033, Cotignola, RA, Italy.
Juan Pablo AbugattasHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Bert AdriaenssensElectrophysiology Unit, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Antwerp, Belgium.
Maysam Al-HousariHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Alexandre AlmoradHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Gezim BalaHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Antonio BisignaniHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Carlo de AsmundisHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Yves De GreefElectrophysiology Unit, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Antwerp, Belgium.
Riccardo MajHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Thiago G OsòrioHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Luigi PannoneHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Bruno SchwagtenElectrophysiology Unit, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Antwerp, Belgium.
Juan SieiraHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Antonio SorgenteHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Erwin StrokerHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Michael WolfElectrophysiology Unit, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Antwerp, Belgium.
Gian-Battista ChierchiaHeart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing, European reference Networks Guard-Heart, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Avenue du Laerbeek 101, 1090, Jette, Brussels, Belgium.
Vrije Universiteit Brussel · BEUniversitair Ziekenhuis Brussel · BEZNA Middelheim Hospital · BEMaria Cecilia Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCryoballoon technology (CB-A) has become a cornerstone of atrial fibrillation (AF) ablation in terms of safety and efficacy. Data regarding CB-A in octogenarians are still scarce and limited to single center experiences. The present study sought to analyze the performances of index CB-A in patients older than 80 years-old referring to 3 high-volume European centers. METHODS AND

resultsWe retrospectively enrolled 95 patients with a median age of 81 [80, 83] years. 62 (65.3%) patients presented with paroxysmal AF and 33 (33.7%) with persistent AF. Mean procedure and fluoroscopy times were 73.8 ± 25.2 and 15.3 ± 7.5 min, respectively. At 12 months and 24 months of follow-up, the overall freedom from AF was 81.1% and 66.6%, respectively. When divided for AF type, freedom from AF was higher in patients with paroxysmal AF (p = 0.007). Cryoballoon ablation was able to significantly improve AF-related symptoms as proven by the significant decrease in EHRA score during the follow-up (p < 0.0001). Phrenic nerve palsy occurred in 8 (8.5%) patients and always resolved during the procedure without affecting procedural outcome. Two major complications occurred (2.1%); one patient experienced pneumonia, successfully treated with antibiotics and non-invasive mechanical ventilation, the latter one experienced acute kidney failure secondary to urosepsis successfully treated by renal replacement therapy.

conclusionsThe present study showed that CB-A is a feasible and effective procedure among octogenarians with a low complication rate. Contemporarily, CB-A can help to alleviate arrhythmia-related symptoms also among this group of subjects.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryPulmonary VeinsAged, 80 and overHumansOctogenariansRecurrenceRetrospective StudiesTreatment OutcomeAtrial fibrillationCryoballoon ablationElderlyOctogenarians

Identifiers

PMID35869379
OpenAlexW4286586372

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.