Evidence map›Paper›PMID 35874168›Full record

ReviewBone reports2022

Non-homologous use of adipose-derived cell and tissue therapies: Osteoarthritis as a case study.

Trivia Frazier, Keith March, Jaime R Garza, Bruce A Bunnell, Kevin F Darr, Emma Rogers, Katie Hamel, Jeffrey M Gimble

Abstract readReview
In one paragraph

Review in Bone reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Osteoarthritis: pathogenic signaling pathways and therapeutic targets.Signal transduction and targeted therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Trivia FrazierObatala Sciences, New Orleans, LA, United States of America.
Keith MarchUniversity of Florida, Gainesville, FL, United States of America.
Jaime R GarzaTulane University, New Orleans, LA, United States of America.
Bruce A BunnellUniversity of North Texas Health Science Center, Ft. Worth, TX, United States of America.
Kevin F DarrCovington Orthopedics Sports Medicine Institute, Covington, LA, United States of America.
Emma RogersObatala Sciences, New Orleans, LA, United States of America.
Katie HamelObatala Sciences, New Orleans, LA, United States of America.
Jeffrey M GimbleObatala Sciences, New Orleans, LA, United States of America.

Funding

BLRD VA I01 BX003888
6 · The paper itself

Abstract

Adipose tissue is widely recognized as an abundant and accessible human tissue that serves as a source of cells and extracellular matrix scaffolds for regenerative surgical applications. Increasingly, orthopedic surgeons are turning to adipose tissue as a resource in their treatment of osteoarthritis and related conditions. In the U.S., the regulatory landscape governing the orthopedic surgical utilization of autologous and allogeneic adipose tissue remains complex. This manuscript reviews the Food and Drug Administration's nomenclature and guidance regarding adipose tissue products. Additionally, it surveys recent pre-clinical and clinical trial literature relating to the application of adipose-derived cells and tissues in the treatment of osteoarthritis.

Indexed as

AdiposeASC, Adipose Stromal/Stem CellsCBER, Center for Biologics Evaluation and ResearchHCT/P, Human Cells, Tissues, and Cell/Tissue related ProductsMFAT, MicroFragmented Adipose TissueMicrofragmented fatOA, OsteoarthritisOsteoarthritisRegenerative medicineRegulatory agencyStromal/stem cellsSVF, Stromal Vascular Fraction Cells

Identifiers

PMID35874168
PMCPMC9305321

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.