Evidence map›Paper›PMID 35874777›Full record

ArticleFrontiers in immunology2022

Comprehensive Flow Cytometric Characterization of Bronchoalveolar Lavage Cells Indicates Comparable Phenotypes Between Asthmatic and Healthy Horses But Functional Lymphocyte Differences.

A Elisabeth Gressler, Sabrina Lübke, Bettina Wagner, Corinna Arnold, Katharina L Lohmann, Christiane L Schnabel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Frontiers in immunology · 2024
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  10. Frontiers in immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

A Elisabeth GresslerInstitute of Immunology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Sabrina LübkeInstitute of Immunology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Bettina WagnerDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
Corinna ArnoldDepartment for Horses, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Katharina L LohmannDepartment for Horses, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Christiane L SchnabelInstitute of Immunology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Leipzig University · DECornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equine asthma (EA) is a highly relevant disease, estimated to affect up to 20% of all horses, and compares to human asthma. The pathogenesis of EA is most likely immune-mediated, yet incompletely understood. To study the immune response in the affected lower airways, mixed leukocytes were acquired through bronchoalveolar lavage (BAL) and the cell populations were analyzed on a single-cell basis by flow cytometry (FC). Samples of 38 horses grouped as respiratory healthy or affected by mild to moderate (mEA) or severe EA (sEA) according to their history, clinical signs, and BAL cytology were analyzed. Using FC, BAL cells and PBMC were comprehensively characterized by cell surface markers

Indexed as

AsthmaCD8-Positive T-LymphocytesAnimalsBronchoalveolar LavageBronchoalveolar Lavage FluidCytokinesFlow CytometryHorsesLeukocytes, MononuclearPhenotypeCytokinescytologyequine asthmaflow cytometryheavesmacrophageRAOT cells

Identifiers

PMID35874777
PMCPMC9296846
OpenAlexW4286630902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.