ArticleFrontiers in bioengineering and biotechnology2022
Visualization of Zika Virus Infection via a Light-Initiated Bio-Orthogonal Cycloaddition Labeling Strategy.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed.
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- Novel benzimidazole-based azine derivatives as potent urease inhibitors: synthesis,Future medicinal chemistry · 2024Article
- Hybrid healthcare unit recommendation system using computational techniques with lung cancer segmentation.Frontiers in medicine · 2024Article
- Exploring novel Apalutamide analogues as potential therapeutics for prostate cancer: design, molecular docking investigations and molecular dynamics simulation.Frontiers in chemistry · 2024Article
- Oxidative stress and senescence in aging kidneys: the protective role of SIRT1.EXCLI journal · 2024Review
- Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling.Iranian journal of basic medical sciences · 2024Article
- Advances in the greener synthesis of chromopyrimidine derivatives by a multicomponent tandem oxidation process.Scientific reports · 2023Article
- Influence of stent-induced vessel deformation on hemodynamic feature of bloodstream inside ICA aneurysms.Biomechanics and modeling in mechanobiology · 2023Article
- Diagnostic ability of deep learning in detection of pancreatic tumour.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zika virus (ZIKV) is a re-emerging flavivirus that leads to devastating consequences for fetal development. It is crucial to visualize the pathogenicity activities of ZIKV ranging from infection pathways to immunity processes, but the accurate labeling of ZIKV remains challenging due to the lack of a reliable labeling technique. We introduce the photo-activated bio-orthogonal cycloaddition to construct a fluorogenic probe for the labeling and visualizing of ZIKV. Via a simple UV photoirradiation, the fluorogenic probes could be effectively labeled on the ZIKV. We demonstrated that it can be used for investigating the interaction between ZIKV and diverse cells and avoiding the autofluorescence phenomenon in traditional immunofluorescence assay. Thus, this bioorthogonal-enabled labeling strategy can serve as a promising approach to monitor and understand the interaction between the ZIKV and host cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.