Evidence map›Paper›PMID 35875835›Full record

ArticlePlant direct2022

The plant endoplasmic reticulum UPRome: A repository and pathway browser for genes involved in signaling networks linked to the endoplasmic reticulum.

Venura Herath, Kaylee Connolly, Anna Roach, Ashish Ausekar, Tracy Persky, Jeanmarie Verchot

Abstract read
In one paragraph

Article in Plant direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Venura HerathDepartment of Plant Pathology & Microbiology Texas A&M University College Station Texas USA.ORCID https://orcid.org/0000-0003-2977-2787
Kaylee ConnollyDepartment of Plant Pathology & Microbiology Texas A&M University College Station Texas USA.
Anna RoachDepartment of Plant Pathology & Microbiology Texas A&M University College Station Texas USA.
Ashish AusekarDivision of Information Technology Texas A&M University College Station Texas USA.
Tracy PerskyDivision of Information Technology Texas A&M University College Station Texas USA.ORCID https://orcid.org/0000-0001-8595-0176
Jeanmarie VerchotDepartment of Plant Pathology & Microbiology Texas A&M University College Station Texas USA.ORCID https://orcid.org/0000-0001-8789-3144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) houses sensors that respond to environmental stress and underly plants' adaptative responses. These sensors transduce signals that lead to changes in nuclear gene expression. The ER to nuclear signaling pathways are primarily attributed to the unfolded protein response (UPR) and are also integrated with a wide range of development, hormone, immune, and stress signaling pathways. Understanding the role of the UPR in signaling network mechanisms that associate with particular phenotypes is crucially important. While UPR-associated genes are the subject of ongoing investigations in a few model plant systems, most remain poorly annotated, hindering the identification of candidates across plant species. This open-source curated database provides a centralized resource of peer reviewed knowledge of ER to nuclear signaling pathways for the plant community. We provide a UPRome interactive viewer for users to navigate through the pathways and to access annotated information. The plant ER UPRome website is located at http://uprome.tamu.edu. We welcome contributions from the researchers studying the ER UPR to incorporate additional genes into the database through the "contact us" page.

Indexed as

curated databaseplant protein interaction mapsplant signal transductionunfolded protein response

Identifiers

PMID35875835
PMCPMC9300056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.