Evidence map›Paper›PMID 35879812›Full record

ArticleBiotechnology and bioengineering2022

Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors.

Joan Sebastián Gallego-Murillo, Giulia Iacono, Luuk A M van der Wielen, Emile van den Akker, Marieke von Lindern, Sebastian Aljoscha Wahl

Open access · bronzeAbstract read
In one paragraph

Article in Biotechnology and bioengineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Joan Sebastián Gallego-MurilloSanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0003-2381-2012
Giulia IaconoSanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, Amsterdam UMC, Amsterdam, The Netherlands.
Luuk A M van der WielenDepartment of Biotechnology, Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands.
Emile van den AkkerSanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, Amsterdam UMC, Amsterdam, The Netherlands.
Marieke von LindernSanquin Research and Landsteiner Laboratory, Department of Hematopoiesis, Amsterdam UMC, Amsterdam, The Netherlands.
Sebastian Aljoscha WahlDepartment of Biotechnology, Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands.
Sanquin · NLComputer Professionals for Social Responsibility · USUniversity of Limerick · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transfusion of donor-derived red blood cells (RBCs) is the most common form of cell therapy. Production of transfusion-ready cultured RBCs (cRBCs) is a promising replacement for the current, fully donor-dependent therapy. A single transfusion unit, however, contains 2 × 10

Indexed as

BioreactorsErythroblastsCell DifferentiationCell ProliferationCells, CulturedHemoglobinsOxygenHemoglobinsOxygencell culturecultured blooderythropoiesisred blood cellscale-upstirred tank bioreactor

Identifiers

PMID35879812
PMCPMC9804173
OpenAlexW4287834736

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.