Evidence map›Paper›PMID 35883642›Full record

SynthesisCells2022

Association of Oral Function and Dysphagia with Frailty and Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.

Kotomi Sakai, Enri Nakayama, Daisuke Yoneoka, Nobuo Sakata, Katsuya Iijima, Tomoki Tanaka, Kuniyoshi Hayashi, Kunihiro Sakuma, Eri Hoshino

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06490705 (Chang Gung Memorial Hospital at Linkou), which is not on this map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06490705 nacompletednot on this map

Chang Gung Memorial Hospital at Linkou

TypeinterventionalSponsorChang Gung Medical FoundationRan2021 to 2024Enrolled88ConditionsDysphagia, OropharyngealArmstongue resistance exercises, tongue strengthening exercises and tongue resistance exercises
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Association between oral health and frailty among older cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kotomi SakaiComprehensive Unit for Health Economic Evidence Review and Decision Support (CHEERS), Research Organization of Science and Technology, Ritsumeikan University, Kyoto 600-8815, Japan.ORCID 0000-0002-8700-9029
Enri NakayamaDepartment of Dysphagia Rehabilitation, Nihon University School of Dentistry, Tokyo 101-8310, Japan.
Daisuke YoneokaInfectious Disease Surveillance Center at the National Institute of Infectious Diseases, Tokyo 162-8640, Japan.ORCID 0000-0002-3525-5092
Nobuo SakataHeisei Medical Welfare Group Research Institute, Tokyo 151-0053, Japan.ORCID 0000-0003-0599-3235
Katsuya IijimaInstitute of Gerontology, The University of Tokyo, Tokyo 113-8654, Japan.ORCID 0000-0003-1339-5681
Tomoki TanakaInstitute of Gerontology, The University of Tokyo, Tokyo 113-8654, Japan.
Kuniyoshi HayashiInstitute of Religion and Culture, Kyoto Women's University, Kyoto 605-8501, Japan.ORCID 0000-0001-9228-0940
Kunihiro SakumaInstitute for Liberal Arts, Environment and Society, Tokyo Institute of Technology, Tokyo 152-8550, Japan.ORCID 0000-0003-1353-0150
Eri HoshinoComprehensive Unit for Health Economic Evidence Review and Decision Support (CHEERS), Research Organization of Science and Technology, Ritsumeikan University, Kyoto 600-8815, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies investigating the associations of oral function and dysphagia with frailty and sarcopenia in community-dwelling older adults are increasing; however, they have not been systematically summarized. We conducted a systematic review to investigate these associations. We searched electronic databases and synthesized relevant data using conventional (frequentist-style) and Bayesian meta-analyses. Twenty-four studies were found to be eligible for our review, including 20 cross-sectional and four prospective cohort studies. Older adults with frailty or sarcopenia had lower tongue pressure, according to the results of conventional meta-analysis (mean difference [95% confidence interval or credible interval]: -6.80 kPa [-10.22 to -3.38] for frailty and -5.40 kPa [-6.62 to -4.17] for sarcopenia) and Bayesian meta-analysis (-6.90 kPa [-9.0 to -4.8] for frailty, -5.35 kPa [-6.78 to -3.89] for sarcopenia). People with frailty had a higher odds ratio (OR) for dysphagia according to the results of conventional meta-analysis (3.99 [2.17 to 7.32]) and Bayesian meta-analysis (1.38 [0.77 to 1.98]). However, the results were inconclusive for people with sarcopenia. A prospective association could not be determined because of the lack of information and the limited number of studies. Decreased oral function and dysphagia can be important characteristics of frailty and sarcopenia in community-dwelling older adults.

Indexed as

Deglutition DisordersFrailtySarcopeniaAgedBayes TheoremCross-Sectional StudiesHumansIndependent LivingPressureProspective StudiesTongueagingdysphagiafrailtyoral functionsarcopenia

Identifiers

PMID35883642
PMCPMC9316124

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.