Evidence map›Paper›PMID 35884901›Full record

ReviewBiomedicines2022

The Extracellular MicroRNAs on Inflammation: A Literature Review of Rodent Studies.

Seri Lee, Jade Heejae Ko, Seung-Nam Kim

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. The immune-modulatory dynamics of exosomes in preeclampsia.Archives of gynecology and obstetrics · 2025
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Seri LeeCollege of Korean Medicine, Dongguk University, Goyang 10326, Korea.
Jade Heejae KoCollege of Korean Medicine, Dongguk University, Goyang 10326, Korea.
Seung-Nam KimCollege of Korean Medicine, Dongguk University, Goyang 10326, Korea.ORCID 0000-0003-3038-727X
Dongguk University · KR

Funding

Korea Health Industry Development Institute HF21C0018National Research Foundation of Korea 2020R1C1C1004107
6 · The paper itself

Abstract

Inflammation is an indispensable biological process stimulated by infection and injuries. Inflammatory mechanisms related to extracellular vesicles (EVs), which are small membrane structures carrying various molecules, were summarized in this review. Emerging evidence from animal studies has highlighted the role of EVs in modulating inflammatory responses, by transporting various molecules involved in host defense. In this review, we have discussed the role of EV miRNAs in inflammation. Rodent studies associated with extracellular miRNAs in inflammatory diseases, published from 2012 to 2022, were explored from PUBMED, EMBASE, and MEDLINE. A total of 95 studies were reviewed. In summary, EV-associated miRNAs play a key role in various diseases, including organ injury, immune dysfunction, neurological disease, metabolic syndrome, vesicular disease, arthritis, cancer, and other inflammatory diseases. Diverse EV-associated miRNAs regulate inflammasome activation and pro- and anti-inflammatory cytokine levels by targeting genes.

Indexed as

arthritiscancerextracellular vesicleimmune dysfunctioninflammationmetabolic syndromeneurological diseaseorgan injury

Identifiers

PMID35884901
PMCPMC9312877
OpenAlexW4284688778

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.