Evidence map›Paper›PMID 35885568›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Novel Survival Features Generated by Clinical Text Information and Radiomics Features May Improve the Prediction of Ischemic Stroke Outcome.

Yingwei Guo, Yingjian Yang, Fengqiu Cao, Wei Li, Mingming Wang, Yu Luo, Jia Guo, Asim Zaman, Xueqiang Zeng, Xiaoqiang Miu and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yingwei GuoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID 0000-0002-3049-8474
Yingjian YangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID 0000-0002-7425-1297
Fengqiu CaoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Wei LiCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Mingming WangDepartment of Radiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200434, China.
Yu LuoDepartment of Radiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200434, China.
Jia GuoDepartment of Psychiatry, Columbia University, New York, NY 10027, USA.ORCID 0000-0003-4803-0279
Asim ZamanCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.ORCID 0000-0002-7723-3684
Xueqiang ZengCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Xiaoqiang MiuCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Longyu LiCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Weiyan QiuCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Yan KangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.

Funding

National Natural Science Foundation of China 62071311The Scientific Research Fund of Liaoning Province of China JL201919The special program for key fields of colleges and universities in Guangdong Province (biomedicine and health) of China 2021ZDZX2008The Stable Support Plan for Colleges and Universities in Shenzhen of China SZWD2021010
6 · The paper itself

Abstract

backgroundAccurate outcome prediction is of great clinical significance in customizing personalized treatment plans, reducing the situation of poor recovery, and objectively and accurately evaluating the treatment effect. This study intended to evaluate the performance of clinical text information (CTI), radiomics features, and survival features (SurvF) for predicting functional outcomes of patients with ischemic stroke.

methodsSurvF was constructed based on CTI and mRS radiomics features (mRSRF) to improve the prediction of the functional outcome in 3 months (90-day mRS). Ten machine learning models predicted functional outcomes in three situations (2-category, 4-category, and 7-category) using seven feature groups constructed by CTI, mRSRF, and SurvF.

resultsFor 2-category, ALL (CTI + mRSRF+ SurvF) performed best, with an mAUC of 0.884, mAcc of 0.864, mPre of 0.877, mF1 of 0.86, and mRecall of 0.864. For 4-category, ALL also achieved the best mAuc of 0.787, while CTI + SurvF achieved the best score with mAcc = 0.611, mPre = 0.622, mF1 = 0.595, and mRe-call = 0.611. For 7-category, CTI + SurvF performed best, with an mAuc of 0.788, mPre of 0.519, mAcc of 0.529, mF1 of 0.495, and mRecall of 0.47.

conclusionsThe above results indicate that mRSRF + CTI can accurately predict functional outcomes in ischemic stroke patients with proper machine learning models. Moreover, combining SurvF will improve the prediction effect compared with the original features. However, limited by the small sample size, further validation on larger and more varied datasets is necessary.

Indexed as

clinical text informationischemic stroke outcomemachine learningradiomics featuressurvival features

Identifiers

PMID35885568
PMCPMC9324145

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.