Evidence map›Paper›PMID 35886983›Full record

ArticleInternational journal of molecular sciences2022

MG-

Stellee M P Biscaia, Cassiano Pires, Francislaine A R Lívero, Daniel L Bellan, Israel Bini, Silvina O Bustos, Renata O Vasconcelos, Alexandra Acco, Marcello Iacomini, Elaine R Carbonero and 10 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Galectin-4 potentiates CD8+ T cell immunity by enhancing MHC-I expression on dendritic cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Stellee M P BiscaiaDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0002-4110-4354
Cassiano PiresDepartment of Chemistry, Biopol, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Francislaine A R LíveroPost-Graduate Program in Medicinal Plants and Phytotherapics in Basic Attention, Parana University (UNIPAR), Umuarama 87502-210, Brazil.ORCID 0000-0001-6533-0850
Daniel L BellanDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Israel BiniDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Silvina O BustosDepartment of Radiology and Oncology, Faculty of Medicine, Center for Translational Research in Oncology (CTO), Cancer Institute of the State of São Paulo, University of São Paulo (USP), São Paulo 01246-000, Brazil.
Renata O VasconcelosDepartment of Radiology and Oncology, Faculty of Medicine, Center for Translational Research in Oncology (CTO), Cancer Institute of the State of São Paulo, University of São Paulo (USP), São Paulo 01246-000, Brazil.
Alexandra AccoDepartment of Pharmacology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Marcello IacominiDepartment of Biochemistry and Molecular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Elaine R CarboneroInstitute of Chemistry, Federal University of Catalão (UFCAT), Catalão 75704-020, Brazil.
Martin K AmstaldenDepartment of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-903, Brazil.
Fábio R KubataDepartment of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-903, Brazil.
Richard D CummingsBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
Marcelo Dias-BaruffiDepartment of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-903, Brazil.ORCID 0000-0002-2039-1884
Fernanda F SimasDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Carolina C OliveiraDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Rilton A FreitasDepartment of Chemistry, Biopol, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Célia Regina Cavichiolo FrancoDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Roger ChammasDepartment of Radiology and Oncology, Faculty of Medicine, Center for Translational Research in Oncology (CTO), Cancer Institute of the State of São Paulo, University of São Paulo (USP), São Paulo 01246-000, Brazil.ORCID 0000-0003-0342-8726
Edvaldo S TrindadeDepartment of Cellular Biology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0002-8051-6298
Universidade Federal do Paraná · BRUniversidade de São Paulo · BRBeth Israel Deaconess Medical Center · USUniversidade Federal do Cariri · BRUniversidade Paranaense · BR

Funding

National Council for Scientific and Technological Development CNPq 305700/2017-0; 315297/2021-2; 310290/2021-0; 312606/2019-2
6 · The paper itself

Abstract

Melanoma is a highly metastatic and rapidly progressing cancer, a leading cause of mortality among skin cancers. The melanoma microenvironment, formed from the activity of malignant cells on the extracellular matrix and the recruitment of immune cells, plays an active role in the development of drug resistance and tumor recurrence, which are clinical challenges in cancer treatment. These tumoral metabolic processes are affected by proteins, including Galectin-3 (Gal-3), which is extensively involved in cancer development. Previously, we characterized a partially methylated mannogalactan (MG-

Indexed as

Antineoplastic AgentsGalectin 3MelanomaSkin NeoplasmsAnimalsDacarbazineLigandsMiceNeoplasm Recurrence, LocalTumor MicroenvironmentAntineoplastic AgentsDacarbazineGalectin 3Ligandsdacarbazinegalectin-3 Lectinmelanomaoxidative stressquartz crystal microbalance (QCM)

Identifiers

PMID35886983
PMCPMC9317553
OpenAlexW4285043826

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.