Evidence map›Paper›PMID 35887060›Full record

ArticleInternational journal of molecular sciences2022

Binding Studies and Lead Generation of Pteridin-7(8

Suparna Ghosh, Seung Joo Cho

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suparna GhoshDepartment of Biomedical Sciences, College of Medicine, Chosun University, Gwangju 501-759, Korea.ORCID 0000-0002-6505-6668
Seung Joo ChoDepartment of Biomedical Sciences, College of Medicine, Chosun University, Gwangju 501-759, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ligand modification by substituting chemical groups within the binding pocket is a popular strategy for kinase drug development. In this study, a series of pteridin-7(8

Indexed as

fms-Like Tyrosine Kinase 3PteridinesBinding SitesLigandsMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingQuantitative Structure-Activity Relationshipfms-Like Tyrosine Kinase 3LigandsPteridines3D-QSARFMS-like tyrosine kinase-3free energy perturbationlinear interaction energyMM-PB/GBSAstructure–activity relationshipumbrella sampling

Identifiers

PMID35887060
PMCPMC9319409

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.