Evidence map›Paper›PMID 35887206›Full record

ReviewInternational journal of molecular sciences2022

NK Cells and Other Cytotoxic Innate Lymphocytes in Colorectal Cancer Progression and Metastasis.

Cinzia Fionda, Gianluca Scarno, Helena Stabile, Rosa Molfetta, Chiara Di Censo, Angela Gismondi, Rossella Paolini, Silvano Sozzani, Angela Santoni, Giuseppe Sciumè

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Cinzia FiondaDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.
Gianluca ScarnoDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.ORCID 0000-0002-2183-5942
Helena StabileDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.
Rosa MolfettaDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.ORCID 0000-0003-2904-6371
Chiara Di CensoDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.
Angela GismondiDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.
Rossella PaoliniDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.ORCID 0000-0001-7605-1531
Silvano SozzaniDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.ORCID 0000-0002-3144-8743
Angela SantoniDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.
Giuseppe SciumèDepartment of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291, 00161 Rome, Italy.ORCID 0000-0003-0131-512X
Istituto Pasteur · ITIstituto Neurologico Mediterraneo · IT

Funding

Institut Pasteur PTR-113-17Istituto Pasteur 2020-366Istituto Pasteur Under 45-213Italian Association for Cancer Research 5x1000-21147Italian Association for Cancer Research IG-24955Italian Association for Cancer Research MFAG-21311Ministero della Salute 20174T7NXL_003
6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common malignancies and leading causes of cancer-related deaths worldwide. Despite its complex pathogenesis and progression, CRC represents a well-fitting example of how the immune contexture can dictate the disease outcome. The presence of cytotoxic lymphocytes, both CD8

Indexed as

Colorectal NeoplasmsLymphocytesAnimalsCD8-Positive T-LymphocytesImmunity, InnateKiller Cells, NaturalMicecolorectal cancerinflammationinnate lymphoid cellsnatural killer cells

Identifiers

PMID35887206
PMCPMC9322916
OpenAlexW4285732887

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.