Evidence map›Paper›PMID 35887846›Full record

ReviewJournal of clinical medicine2022

Dyslipidemia in Transplant Patients: Which Therapy?

Gabriella Iannuzzo, Gianluigi Cuomo, Anna Di Lorenzo, Maria Tripaldella, Vania Mallardo, Paola Iaccarino Idelson, Caterina Sagnelli, Antonello Sica, Massimiliano Creta, Javier Baltar and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Gabriella IannuzzoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-7392-5544
Gianluigi CuomoDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.
Anna Di LorenzoDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.
Maria TripaldellaDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.
Vania MallardoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.
Paola Iaccarino IdelsonDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-2205-5446
Caterina SagnelliDepartment of Mental Health and Public Medicine, University of Campania "Luigi Vanvitelli", Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-6413-7810
Antonello SicaDepartment of Precision Medicine University of Campania "Luigi Vanvitelli", Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-8676-4620
Massimiliano CretaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-2082-3330
Javier BaltarServicio de Cirugía General, Xerencia de Xestión Integrada de Santiago (XXIS/SERGAS), 15706 Santiago de Compostela, Spain.
Felice CrocettoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-4315-7660
Alessandro BrescianiDepartment of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.
Marco GentileDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-3744-6375
Armando CalogeroServicio de Cirugía General, Xerencia de Xestión Integrada de Santiago (XXIS/SERGAS), 15706 Santiago de Compostela, Spain.
Francesco GiallauriaDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-4119-9397
University of Naples Federico II · ITFundación Pública Galega de Medicina Xenómica · ESUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is the most important cause of death worldwide in recent years; an increasing trend is also shown in organ transplant patients subjected to immunosuppressive therapies, in which cardiovascular diseases represent one of the most frequent causes of long-term mortality. This is also linked to immunosuppressant-induced dyslipidemia, which occurs in 27 to 71% of organ transplant recipients. The aim of this review is to clarify the pathophysiological mechanisms underlying dyslipidemia in patients treated with immunosuppressants to identify immunosuppressive therapies which do not cause dyslipidemia or therapeutic pathways effective in reducing hypercholesterolemia, hypertriglyceridemia, or both, without further adverse events.

Indexed as

cardiovascular diseasedyslipidemiaimmunosuppressive therapyorgan transplant

Identifiers

PMID35887846
PMCPMC9318180
OpenAlexW4285596353

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.