Evidence map›Paper›PMID 35888125›Full record

ReviewLife (Basel, Switzerland)2022

Mass Spectrometry Imaging Spatial Tissue Analysis toward Personalized Medicine.

Juliana P L Gonçalves, Christine Bollwein, Kristina Schwamborn

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. State-of-the-Art and Future Directions in Structural Proteomics.Molecular & cellular proteomics : MCP · 2025
    Review
  6. Spatial pharmacology using mass spectrometry imaging.Trends in pharmacological sciences · 2024
    Review
  7. Article
  8. New Challenges for Anatomists in the Era of Omics.Diagnostics (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Juliana P L GonçalvesInstitute of Pathology, School of Medicine, Technical University of Munich, Trogerstraße 18, 81675 Munich, Germany.ORCID 0000-0002-6634-9876
Christine BollweinInstitute of Pathology, School of Medicine, Technical University of Munich, Trogerstraße 18, 81675 Munich, Germany.
Kristina SchwambornInstitute of Pathology, School of Medicine, Technical University of Munich, Trogerstraße 18, 81675 Munich, Germany.
Technical University of Munich · DEDeutschen Konsortium für Translationale Krebsforschung · DE

Funding

German Cancer Aid 70113450
6 · The paper itself

Abstract

Novel profiling methodologies are redefining the diagnostic capabilities and therapeutic approaches towards more precise and personalized healthcare. Complementary information can be obtained from different omic approaches in combination with the traditional macro- and microscopic analysis of the tissue, providing a more complete assessment of the disease. Mass spectrometry imaging, as a tissue typing approach, provides information on the molecular level directly measured from the tissue. Lipids, metabolites, glycans, and proteins can be used for better understanding imbalances in the DNA to RNA to protein translation, which leads to aberrant cellular behavior. Several studies have explored the capabilities of this technology to be applied to tumor subtyping, patient prognosis, and tissue profiling for intraoperative tissue evaluation. In the future, intercenter studies may provide the needed confirmation on the reproducibility, robustness, and applicability of the developed classification models for tissue characterization to assist in disease management.

Indexed as

cancer researchmass spectrometry imagingpathologypersonalized medicineproteomicstissue typing

Identifiers

PMID35888125
PMCPMC9318569
OpenAlexW4285090207

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.