Evidence mapPaperPMID 35888989Full record

ArticleMicroorganisms2022

Novel Unspecific Peroxygenase from

Rosalie König, Jan Kiebist, Johannes Kalmbach, Robert Herzog, Kai-Uwe Schmidtke, Harald Kellner, René Ullrich, Nico Jehmlich, Martin Hofrichter, Katrin Scheibner

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Rapid screening system to identify unspecific peroxygenase activity.Clinical hemorheology and microcirculation · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rosalie KönigInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Jan KiebistInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Johannes KalmbachInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Robert HerzogUnit of Environmental Biotechnology, TU Dresden-International Institute Zittau, Markt 23, 02763 Zittau, Germany.
Kai-Uwe SchmidtkeInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Harald KellnerUnit of Environmental Biotechnology, TU Dresden-International Institute Zittau, Markt 23, 02763 Zittau, Germany.
René UllrichUnit of Environmental Biotechnology, TU Dresden-International Institute Zittau, Markt 23, 02763 Zittau, Germany.ORCID 0000-0002-9165-6341
Nico JehmlichDepartment of Molecular Systems Biology, Helmholtz-Centre for Environmental Research, UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.ORCID 0000-0002-5638-6868
Martin HofrichterUnit of Environmental Biotechnology, TU Dresden-International Institute Zittau, Markt 23, 02763 Zittau, Germany.ORCID 0000-0001-5174-7604
Katrin ScheibnerInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Brandenburg University of Technology Cottbus-Senftenberg · DEInternational University Institute · DEFraunhofer Institute for Cell Therapy and Immunology · DEHelmholtz Centre for Environmental Research · DE

Funding

Federal Ministry of Education and Research 031B0831Federal Ministry of Education and Research 03WIR30IL1Ministerium für Wissenschaft, Forschung und Kultur 22-F241-03- 520 FhG/005/001Ministerium für Wissenschaft, Forschung und Kultur GZ: INST 522 263/88-1 LAGG
6 · The paper itself

Abstract

Lipid mediators, such as epoxidized or hydroxylated eicosanoids (EETs, HETEs) of arachidonic acid (AA), are important signaling molecules and play diverse roles at different physiological and pathophysiological levels. The EETs and HETEs formed by the cytochrome P450 enzymes are still not fully explored, but show interesting anti-inflammatory properties, which make them attractive as potential therapeutic target or even as therapeutic agents. Conventional methods of chemical synthesis require several steps and complex separation techniques and lead only to low yields. Using the newly discovered unspecific peroxygenase

Indexed as

biocatalysisEETseicosanoidsHETEshuman drug metaboliteslipid mediatorsTanUPOunspecific peroxygenases

Identifiers

PMID35888989
PMCPMC9322767
OpenAlexW4283312358

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.