Evidence mapPaperPMID 35889348Full record

ReviewMolecules (Basel, Switzerland)2022

Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review.

Tong Chen, Fan Jia, Yue Yu, Wufan Zhang, Chaoying Wang, Shiqin Zhu, Nana Zhang, Xinmin Liu

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603505 (Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603505 phase1completednot on this mapstarted 2025, after this paper: background citation

Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome (PCOS)

TypeinterventionalSponsorJinnah Sindh Medical UniversityRan2025 to 2026Enrolled116ConditionsPolycystic Ovarian Syndrome (PCOS), Infertility, Metabolic DisordersArmsHerbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Quercetin and polycystic ovary syndrome.Frontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tong ChenDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.ORCID 0000-0003-2501-3847
Fan JiaDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Yue YuDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.ORCID 0000-0002-1287-3349
Wufan ZhangDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Chaoying WangDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Shiqin ZhuDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Nana ZhangDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Xinmin LiuDepartment of Gynecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing University of Chinese Medicine · CN

Funding

China Academy of Chinese Medical Sciences C120221A02404National Natural Science Foundation of China 81674011
6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women's physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS.

Indexed as

Insulin ResistancePolycystic Ovary SyndromeAndrogensFemaleHumansOvulationQuercetinAndrogensQuercetinantioxidantmechanismpolycystic ovary syndromequercetin

Identifiers

PMID35889348
PMCPMC9325244
OpenAlexW4285393766

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.