Evidence map›Paper›PMID 35889927›Full record

ReviewNutrients2022

Gut Microbiota in Psoriasis.

Mihaela Cristina Buhaș, Laura Ioana Gavrilaș, Rareș Candrea, Adrian Cătinean, Andrei Mocan, Doina Miere, Alexandru Tătaru

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07475299 (The Impact of a Synbiotic Supplement Containing Botanical Extracts and Multiple Probiotic Strains on Gut Microbiota Balance in Patients With Irritable Bowel Syndrome), which is not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07475299 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Impact of a Synbiotic Supplement Containing Botanical Extracts and Multiple Probiotic Strains on Gut Microbiota Balance in Patients With Irritable Bowel Syndrome: A Pilot Prospective Interventional Study

TypeinterventionalSponsorIuliu Hatieganu University of Medicine and PharmacyRan2026 to 2027Enrolled8ConditionsIrritable Bowel Syndrome (IBS)ArmsSynbiotic supplement containing probiotic strains, botanical extracts, magnesium, vitamin B1, and L-theanine designed to support gut microbiota balance.
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Gut-derived genistein fromGut microbes · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mihaela Cristina BuhașDepartment of Dermatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400423 Cluj-Napoca, Romania.
Laura Ioana GavrilașDepartment of Bromatology, Hygiene, Nutrition, "Iuliu Hatieganu" University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania.
Rareș CandreaBachelor Program in Nutrition and Dietetics, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.
Adrian CătineanDepartment of Internal Medicine/Gastroenterology, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.ORCID 0000-0002-6327-6608
Andrei MocanDepartment of Pharmaceutical Botany, "Iuliu Hatieganu" University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania.ORCID 0000-0001-5848-8457
Doina MiereDepartment of Bromatology, Hygiene, Nutrition, "Iuliu Hatieganu" University of Medicine and Pharmacy, 23 Marinescu Street, 400337 Cluj-Napoca, Romania.ORCID 0000-0001-5029-5060
Alexandru TătaruDepartment of Dermatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400423 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth and defective differentiation. The link between the gut microbiota and immune system regulation opened a novel angle to understand the pathogenesis of many chronic multifactorial diseases, including psoriasis. Current evidence suggests that modulation of the gut microbiota, both through dietary approaches and through supplementation with probiotics and prebiotics, could represent a novel therapeutic approach. The present work aims to highlight the latest scientific evidence regarding the microbiome alterations of psoriatic patients, as well as state of the art insights in terms of microbiome-targeted therapies as promising preventive and therapeutic tools for psoriasis.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaProbioticsPsoriasisSkin DiseasesHumansPrebioticsPrebioticsdietary approachesmicrobiotaprebioticsprobioticspsoriasis

Identifiers

PMID35889927
PMCPMC9321451
OpenAlexW4286500727

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.