Evidence map›Paper›PMID 35890156›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Aspects of Antiviral Strategies Based on Different Phototherapy Approaches: Hit by the Light.

Hannah Kunstek, Fanny Vreken, Aminata Keita, Michael R Hamblin, Florence Dumarçay, Mihayl Varbanov

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Membrane-Targeting Antivirals.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Near-Infrared Dyes: Towards Broad-Spectrum Antivirals.International journal of molecular sciences · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Hannah KunstekL2CM, Université de Lorraine, Centre National de la Recherche Scientifique (CNRS), 54000 Nancy, France.
Fanny VrekenL2CM, Université de Lorraine, Centre National de la Recherche Scientifique (CNRS), 54000 Nancy, France.
Aminata KeitaL2CM, Université de Lorraine, Centre National de la Recherche Scientifique (CNRS), 54000 Nancy, France.
Michael R HamblinLaser Research Centre, University of Johannesburg, Doornfontein 2028, South Africa.ORCID 0000-0001-6431-4605
Florence DumarçayL2CM, Université de Lorraine, Centre National de la Recherche Scientifique (CNRS), 54000 Nancy, France.
Mihayl VarbanovL2CM, Université de Lorraine, Centre National de la Recherche Scientifique (CNRS), 54000 Nancy, France.
Centre National de la Recherche Scientifique · FRUniversité de Tours · FRUniversity of Johannesburg · ZA

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which caused the COVID-19 pandemic spreading around the world from late 2019, served as a ruthless reminder of the threat viruses pose to global public health. The synthesis of new antiviral drugs, as well as repurposing existing products, is a long-term ongoing process which has challenged the scientific community. One solution could be an effective, accessible, and rapidly available antiviral treatment based on phototherapy (PT). PT has been used to treat several diseases, and relies on the absorption of light by endogenous molecules or exogenous photosensitizers (PS). PT has often been used in cancer treatment and prophylaxis, and as a complement to established chemotherapy and immunotherapy in combined therapeutic strategy. Besides significant applications in anticancer treatment, studies have demonstrated the beneficial impact of PT on respiratory, systemic, emerging, and oncogenic viral infections. The aim of this review was to highlight the potential of PT to combat viral infections by summarizing current progress in photodynamic, photothermal, and photoacoustic approaches. Attention is drawn to the virucidal effect of PT on systemic viruses such as the human immunodeficiency virus and human herpes viruses, including the causative agent of Kaposi sarcoma, human herpes virus (HHV8). PT has good potential for disinfection in anti-norovirus research and against pandemic viruses like SARS-CoV-2.

Indexed as

antiviralPDTphotoacousticphototherapyphotothermalvirus

Identifiers

PMID35890156
PMCPMC9316526
OpenAlexW4285394044

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.