Evidence map›Paper›PMID 35890273›Full record

ReviewPharmaceutics2022

Recent Advances in Hydrogel-Mediated Nitric Oxide Delivery Systems Targeted for Wound Healing Applications.

Gina Tavares, Patrícia Alves, Pedro Simões

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gina TavaresUniversity of Coimbra, Chemical Process Engineering and Forest Products Research Centre, Department of Chemical Engineering, Rua Sílvio Lima, 3030-790 Coimbra, Portugal.ORCID 0000-0003-2510-8790
Patrícia AlvesUniversity of Coimbra, Chemical Process Engineering and Forest Products Research Centre, Department of Chemical Engineering, Rua Sílvio Lima, 3030-790 Coimbra, Portugal.ORCID 0000-0002-8943-8329
Pedro SimõesUniversity of Coimbra, Chemical Process Engineering and Forest Products Research Centre, Department of Chemical Engineering, Rua Sílvio Lima, 3030-790 Coimbra, Portugal.ORCID 0000-0002-5068-950X

Funding

Fundação para a Ciência e Tecnologia UI/BD/150855/2021Fundação para a Ciência e Tecnologia UIDB/EQU/00102/2020
6 · The paper itself

Abstract

Despite the noticeable evolution in wound treatment over the centuries, a functional material that promotes correct and swift wound healing is important, considering the relative weight of chronic wounds in healthcare. Difficult to heal in a fashionable time, chronic wounds are more prone to infections and complications thereof. Nitric oxide (NO) has been explored for wound healing applications due to its appealing properties, which in the wound healing context include vasodilation, angiogenesis promotion, cell proliferation, and antimicrobial activity. NO delivery is facilitated by molecules that release NO when prompted, whose stability is ensured using carriers. Hydrogels, popular materials for wound dressings, have been studied as scaffolds for NO storage and delivery, showing promising results such as enhanced wound healing, controlled and sustained NO release, and bactericidal properties. Systems reported so far regarding NO delivery by hydrogels are reviewed.

Indexed as

chronic woundshydrogelNitric oxidewound dressing

Identifiers

PMID35890273
PMCPMC9315818

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.