Evidence map›Paper›PMID 35892340›Full record

ReviewBiomolecules2022

Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease.

Ewan Douglas Fowler, Spyros Zissimopoulos

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Calcium release channel deficiency syndrome in patients diagnosed with idiopathic ventricular fibrillation and decedents classified as sudden unexplained death in the young.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Structural Integrity of RyR2 Clusters Controls Cardiac Calcium Leak.bioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Heart on Fire: UnmaskingMethodist DeBakey cardiovascular journal · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Translational pediatrics · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ewan Douglas FowlerSchool of Biosciences, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF10 3AX, UK.ORCID 0000-0001-5580-2156
Spyros ZissimopoulosInstitute of Life Science, Swansea University Medical School, Swansea University, Swansea SA2 8PP, UK.ORCID 0000-0001-5196-9450
Cardiff University · GBSwansea University · GB

Funding

British Heart Foundation FS/IBSRF/21/25071British Heart Foundation PG/21/10657
6 · The paper itself

Abstract

The ryanodine receptor (RyR2) has a critical role in controlling Ca

Indexed as

Arrhythmias, CardiacCalciumRyanodine Receptor Calcium Release ChannelCalcium SignalingHumansMutationMyocytes, CardiacSarcoplasmic ReticulumCalciumRyanodine Receptor Calcium Release ChannelRyR2 protein, humanarrhythmiascalcium release deficiency syndromecalcium sparkscatecholaminergic polymorphic ventricular tachycardiadelayed afterdepolarizationsearly afterdepolarizationslong QT syndromeryanodine receptor

Identifiers

PMID35892340
PMCPMC9394283
OpenAlexW4288038896

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.