Evidence map›Paper›PMID 35892791›Full record

ArticleFoods (Basel, Switzerland)2022

An Insulin Receptor-Binding Multifunctional Protein from

Izael Costa, Mayara Lima, Amanda Medeiros, Lucas Bezerra, Paula Santos, Alexandre Serquiz, Maíra Lima, Gerciane Oliveira, Elizeu Santos, Bruna Maciel and 2 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Izael CostaBiochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.
Mayara LimaBiochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.
Amanda MedeirosBiochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.
Lucas BezerraChemistry Postgraduate Program, Science Center, Federal University of Ceará, Fortaleza 60020-903, Brazil.
Paula SantosFederal Institute of Education, Science and Technology of Rio Grande do Norte, Macau 59500-000, Brazil.
Alexandre SerquizNutrition Course, University Center of Rio Grande do Norte, Natal 59014-545, Brazil.
Maíra LimaVeterinary Medicine Course, Potiguar University, Natal 59056-000, Brazil.
Gerciane OliveiraNutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.
Elizeu SantosBiochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.ORCID 0000-0003-4372-2161
Bruna MacielNutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.ORCID 0000-0002-0724-1961
Norberto MonteiroChemistry Postgraduate Program, Science Center, Federal University of Ceará, Fortaleza 60020-903, Brazil.
Ana Heloneida MoraisBiochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59075-000, Brazil.ORCID 0000-0002-6460-911X

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001National Council for Scientific and Technological Development 426116/2018-6
6 · The paper itself

Abstract

The objectives of this study were to evaluate the hypoglycemic effect of the trypsin inhibitor isolated from tamarind seeds (TTI) in an experimental model of T2DM and the in silico interaction between the conformational models of TTI 56/287 and the insulin receptor (IR). After inducing T2DM, 15 male Wistar rats were randomly allocated in three groups (

Indexed as

hypoglycemic agentmolecular docking simulationplant proteinstamarindtrypsin inhibitor

Identifiers

PMID35892791
PMCPMC9332146

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.