Evidence map›Paper›PMID 35894768›Full record

Trial reportAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2022

The effects of aerobic exercise combined with resistance training on inflammatory factors and heart rate variability in middle-aged and elderly women with type 2 diabetes mellitus.

Xiaoyun Su, Jiping He, Jianmei Cui, Hongmei Li, Jie Men

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  5. The effects of aerobic exercise combined with resistance training on inflammatory factors and heart rate variability in middle-aged and elderly women with type 2 diabetes mellitus.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaoyun SuDepartment of Nursing, Fenyang College Shanxi Medical University, Fenyang, China.
Jiping HeDepartment of Anatomy, Fenyang College Shanxi Medical University, Fenyang, China.ORCID 0000-0002-4472-2545
Jianmei CuiDepartment of Sports, North University of China, Taiyuan, China.
Hongmei LiDepartment of Nursing, Fenyang College Shanxi Medical University, Fenyang, China.
Jie MenDepartment of Sports, Fenyang College Shanxi Medical University, Fenyang, China.
Shanxi Medical University · CNNorth University of China · CN

Funding

Shanxi Province education science "13th five-year plan" project GH-19211
6 · The paper itself

Abstract

objectiveThis study investigated the effects of aerobic exercise combined with resistance training on serum inflammatory factors and heart rate variability (HRV) in women with type 2 diabetes mellitus (T2DM).

methodsA total of 30 patients with diabetic cardiovascular autonomic neuropathy (DCAN) were randomly divided into a control group (n = 15) and an exercise group (n = 15). The control group was treated with routine hypoglycemic drugs, while the exercise group was treated with routine hypoglycemic drugs + resistance training (AE + RT). The levels of fasting plasma glucose (FBG), two-hour plasma glucose (2hPG), serum inflammatory factors C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) were measured before and after the intervention. The HRV was evaluated by 24-h ambulatory electrocardiogram.

resultsAfter the intervention, the levels of FBG, 2hPG, serum inflammatory factors, IL-6 and TNF-α in the exercise group were significantly lower than those in the control group (p < .05) with no significant differences in serum CRP (p > .05). After the intervention, the HRV time domain and frequency domain indexes in the two groups were significantly improved compared with those before the exercise experiment (p < .01) and with no significant difference in (lnlf) (p > .05). The time-domain indexes, i.e., SDNN and RMSSD, as well as the frequency domain index, i.e., (lnhf), were significantly higher in the exercise group than in the control group, whereas lnlf/lnhf were significantly lower than those in the control group (p < .05).

conclusionsCompared with routine hypoglycemic drug therapy, combining aerobic exercise and resistance training helped to reduce the level of blood glucose and serum inflammatory factors in T2DM patients with DCAN, and improved autonomic nerve function.

Indexed as

Diabetes Mellitus, Type 2Resistance TrainingAgedBlood GlucoseElectrocardiographyExerciseExercise TherapyFemaleHeart RateHumansHypoglycemic AgentsInterleukin-6Middle AgedTumor Necrosis Factor-alphaBlood GlucoseHypoglycemic AgentsInterleukin-6Tumor Necrosis Factor-alphaaerobic exercise and resistance exerciseblood glucoseheart rate variabilityinflammatory cytokinestype 2 diabetes

Identifiers

PMID35894768
PMCPMC9674784
OpenAlexW4288067660

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.