Evidence map›Paper›PMID 35895103›Full record

ReviewPflugers Archiv : European journal of physiology2022

Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology.

David Pearce, Anna D Manis, Viatcheslav Nesterov, Christoph Korbmacher

Open access · hybridAbstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
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  11. Impact of aldosterone deficiency on the development of diuretic resistance in mice.Pflugers Archiv : European journal of physiology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Revisiting voltage-coupled HAmerican journal of physiology. Renal physiology · 2024
    Review
  18. Mineralocorticoid Receptor and Sleep Quality in Chronic Kidney Disease.International journal of molecular sciences · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

David PearceDepartment of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA. david.pearce@ucsf.edu.
Anna D ManisDepartment of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
Viatcheslav NesterovInstitut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany.
Christoph KorbmacherInstitut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of California, San Francisco · US

Funding

SGK Regulation of Epithelial Sodium TransportR01DK056695 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAVID PEARCE · 2000 to 2026
$8.1M
NIDDK NIH HHS R01 DK056695
6 · The paper itself

Abstract

Regulated Na

Indexed as

Epithelial Sodium ChannelsKidney Tubules, DistalAldosteroneElectrolytesHomeostasisIon TransportSodiumSolute Carrier Family 12, Member 3AldosteroneElectrolytesEpithelial Sodium ChannelsSodiumSolute Carrier Family 12, Member 311ß-hydroxysteroid dehydrogenase type 2 (11ßHSD2)AldosteroneAldosterone-sensitive distal nephron (ASDN)Connecting tubule (CNT)Cortical collecting duct (CCD)Early distal convoluted tubule (DCT1)Epithelial sodium channel (ENaC)Kinase 1 and 4 (WNK1 and WNK4)Late distal convoluted tubule (DCT2)Mineralocorticoid receptor (MR)Na+-Cl− cotransporter (NCC)Renal outer medullary K+ channel (ROMK)Serum and glucocorticoid-regulated kinase 1 (SGK1); mTOR complex 2 (mTORC2)With no lysine

Identifiers

PMID35895103
PMCPMC9338908
OpenAlexW4288176202

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.