Evidence mapPaperPMID 35896208Full record

SynthesisThe European respiratory journal2022

Increasing physical activity in severe asthma: a systematic review and meta-analysis.

Rebecca F McLoughlin, Vanessa L Clark, Paola D Urroz, Peter G Gibson, Vanessa M McDonald

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The European respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Asthma: Biomedical and Psychobiological Perspectives.Biopsychosocial science and medicine · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Patient-centred outcomes in severe asthma: fatigue, sleep, physical activity and work.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rebecca F McLoughlinNational Health and Medical Research Council, Centre of Excellence in Treatable Traits, Newcastle, Australia.ORCID https://orcid.org/0000-0002-9874-4862
Vanessa L ClarkNational Health and Medical Research Council, Centre of Excellence in Treatable Traits, Newcastle, Australia.ORCID https://orcid.org/0000-0003-3450-5843
Paola D UrrozNational Health and Medical Research Council, Centre of Excellence in Treatable Traits, Newcastle, Australia.ORCID https://orcid.org/0000-0003-0192-2245
Peter G GibsonNational Health and Medical Research Council, Centre of Excellence in Treatable Traits, Newcastle, Australia.ORCID https://orcid.org/0000-0001-5865-489X
Vanessa M McDonaldNational Health and Medical Research Council, Centre of Excellence in Treatable Traits, Newcastle, Australia vanessa.mcdonald@newcastle.edu.au.ORCID https://orcid.org/0000-0001-9890-3408
Hunter Medical Research Institute · AUJohn Hunter Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhysical inactivity is common in asthma and is recognised as an important modifiable risk for poor clinical outcomes such as impaired asthma control and health-related quality of life (HRQoL). Despite evidence supporting the role of physical activity in reducing the risk of these outcomes, little is known about optimal interventions for increasing physical activity in those with severe disease. This systematic review and meta-analysis evaluates the effectiveness of interventions in increasing physical activity in severe asthma.

methodsMEDLINE, the Cumulative Index to Nursing and Allied Health Literature, Embase, PubMed, Informit, SPORTDiscus and Cochrane databases were searched up to September 2021 for physical activity-based intervention studies that assessed physical activity outcomes (

resultsFour randomised controlled trials (all 12 weeks in duration) including 176 adults with moderate-to-severe asthma were included. An increase in physical activity was reported with a moderate-vigorous intensity aerobic and resistance training intervention (steps per day and time spent undertaking physical activity), and an unsupervised pedometer-based intervention (steps per day). Meta-analyses showed that physical activity interventions had an overall positive effect on steps per day (mean difference (MD) 1588, 95% CI 399-2778; p

conclusionWhile there is some evidence supporting the effectiveness of interventions in improving physical activity in adults with severe asthma, higher-quality, large-scale studies of longer duration are needed to determine the optimal intervention.

Indexed as

AsthmaQuality of LifeActigraphyAdultExerciseHumansSedentary Behavior

Identifiers

PMID35896208
PMCPMC9753478
OpenAlexW4288074860

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.