Evidence map›Paper›PMID 35897702›Full record

ArticleInternational journal of molecular sciences2022

Modeling Lung Carcinoids with Zebrafish Tumor Xenograft.

Silvia Carra, Germano Gaudenzi, Alessandra Dicitore, Maria Celeste Cantone, Alice Plebani, Davide Saronni, Silvia Zappavigna, Michele Caraglia, Alessia Candeo, Andrea Bassi and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Interaction Between theInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Carcinoid Syndrome: Preclinical Models and Future Therapeutic Strategies.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Silvia CarraLaboratory of Endocrine and Metabolic Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.
Germano GaudenziLaboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.
Alessandra DicitoreDepartment of Medical Biotechnology and Translational Medicine, University of Milan, 20100 Milan, Italy.ORCID 0000-0003-0887-5242
Maria Celeste CantoneLaboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.
Alice PlebaniLaboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.
Davide SaronniDepartment of Medical Biotechnology and Translational Medicine, University of Milan, 20100 Milan, Italy.
Silvia ZappavignaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4787-3776
Michele CaragliaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-2408-6091
Alessia CandeoDepartment of Physics, Politecnico di Milano, 20133 Milan, Italy.
Andrea BassiDepartment of Physics, Politecnico di Milano, 20133 Milan, Italy.
Luca PersaniLaboratory of Endocrine and Metabolic Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.ORCID 0000-0003-2068-9581
Giovanni VitaleLaboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, 20100 Milan, Italy.ORCID 0000-0003-2478-683X
IRCCS Istituto Auxologico Italiano · ITUniversity of Milan · ITPolitecnico di Milano · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

Italian Ministry of Health IRCCS funding Ricerca CorrenteNeuroendocrine Tumor Research Foundation (NETRF) Pilot Study 2019
6 · The paper itself

Abstract

Lung carcinoids are neuroendocrine tumors that comprise well-differentiated typical (TCs) and atypical carcinoids (ACs). Preclinical models are indispensable for cancer drug screening since current therapies for advanced carcinoids are not curative. We aimed to develop a novel in vivo model of lung carcinoids based on the xenograft of lung TC (NCI-H835, UMC-11, and NCI-H727) and AC (NCI-H720) cell lines and patient-derived cell cultures in

Indexed as

Carcinoid TumorCarcinoma, NeuroendocrineLung NeoplasmsAnimalsHeterograftsHumansLungNeovascularization, PathologicZebrafishangiogenesisatypical carcinoidlung carcinoidsmetastasisneuroendocrine tumorssulfatinibtumor xenografttypical carcinoidzebrafish

Identifiers

PMID35897702
PMCPMC9330857
OpenAlexW4287010175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.