Evidence mapPaperPMID 35903327Full record

ArticleFrontiers in pharmacology2022

Nanostructured Lipid Carrier-Based Delivery of Pioglitazone for Treatment of Type 2 Diabetes.

Umair Ilyas, Muhammad Asif, Minglian Wang, Reem Altaf, Hajra Zafar, Mirza Muhammad Faran Ashraf Baig, Ana Cláudia Paiva-Santos, Muhammad Abbas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Solid lipid nanoparticles as carriers forFrontiers in aging neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Umair IlyasRiphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Muhammad AsifRiphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Minglian WangFaculty of Environment and Life Science, Beijing University of Technology, Bejing, China.
Reem AltafDepartment of Pharmacy, Iqra University Islamabad Campus, Islamabad, Pakistan.
Hajra ZafarSchool of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Mirza Muhammad Faran Ashraf BaigLaboratory of Biomedical Engineering for Novel Bio-Functional, and Pharmaceutical Nano-Materials, Prince Philip Dental Hospital, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Ana Cláudia Paiva-SantosDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
Muhammad AbbasRiphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Riphah International University · PKBeijing University of Technology · CNIqra University · PKShanghai Jiao Tong University · CNUniversity of Coimbra · PTUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pioglitazone (PGZ) is utilized as a therapeutic agent in the management of (type 2) diabetes to control blood glucose levels. The existing research work was intended to make and optimize PGZ-containing NLCs (nanostructured lipid carriers). The fabricated nanostructured lipid carrier preparation was optimized by using different concentrations of the surfactants (Tween 80 and Span 80) and solid lipid (Compritol

Indexed as

diabetesnanoparticlesNLCspioglitazonepoor aqueous solubility

Identifiers

PMID35903327
PMCPMC9315350
OpenAlexW4285041111

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.