Evidence map›Paper›PMID 35904162›Full record

ReviewLab on a chip2022

Machine learning for microfluidic design and control.

David McIntyre, Ali Lashkaripour, Polly Fordyce, Douglas Densmore

Abstract readReview
In one paragraph

Review in Lab on a chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
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  15. Article
  16. HarnessingSensors (Basel, Switzerland) · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Machine-Learning-Aided Advanced Electrochemical Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David McIntyreBiomedical Engineering Department, Boston University, MA, USA.ORCID 0000-0003-3508-4139
Ali LashkaripourDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-1734-9634
Polly FordyceDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9505-0638
Douglas DensmoreBiological Design Center, Boston University, Boston, MA, USA. dougd@bu.edu.ORCID 0000-0002-7666-6808

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
Leveraging spectral encoding for high dimensional biological multiplexingDP2GM123641 · NIGMS · STANFORD UNIVERSITY · PI FORDYCE, POLLY MORRELL · 2016 to 2016
$2.4M
COMPUTATIONAL METHODS FOR PROTEOMIC ANALYSISK22HG000044 · NHGRI · UNIVERSITY OF UTAH · PI GIDDINGS, MORGAN CORINNE · 2000 to 2005
$1.3M
NHGRI NIH HHS K22 HG000044NHGRI NIH HHS T32 HG000044NIGMS NIH HHS DP2 GM123641
6 · The paper itself

Abstract

Microfluidics has developed into a mature field with applications across science and engineering, having particular commercial success in molecular diagnostics, next-generation sequencing, and bench-top analysis. Despite its ubiquity, the complexity of designing and controlling custom microfluidic devices present major barriers to adoption, requiring intuitive knowledge gained from years of experience. If these barriers were overcome, microfluidics could miniaturize biological and chemical research for non-experts through fully-automated platform development and operation. The intuition of microfluidic experts can be captured through machine learning, where complex statistical models are trained for pattern recognition and subsequently used for event prediction. Integration of machine learning with microfluidics could significantly expand its adoption and impact. Here, we present the current state of machine learning for the design and control of microfluidic devices, its possible applications, and current limitations.

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsHigh-Throughput Nucleotide SequencingLab-On-A-Chip DevicesMachine Learning

Identifiers

PMID35904162
PMCPMC9361804

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.