Evidence map›Paper›PMID 35908937›Full record

ArticleThe Journal of veterinary medical science2022

Bovine leukemia virus-associated B cell lymphoma with severe pleomorphism in a steer.

Akiyo Hagiwara, Asami Nishimori, Shinichi Hatama, Osamu Mikami, Yoshiharu Ishikawa, Koichi Kadota

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Akiyo HagiwaraSaitama Prefecture Meat Inspection Center, Saitama, Japan.
Asami NishimoriNational Institute of Animal Health, National Agriculture and Food Research Organization, Ibaraki, Japan.
Shinichi HatamaNational Institute of Animal Health, National Agriculture and Food Research Organization, Ibaraki, Japan.
Osamu MikamiSapporo Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, Hokkaido, Japan.
Yoshiharu IshikawaSapporo Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, Hokkaido, Japan.
Koichi KadotaSapporo Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, Hokkaido, Japan.
National Institute of Animal Health · JPNational Agriculture and Food Research Organization · JPSaitama Prefecture · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined a 26-month-old steer with neoplastic lesions in the spleen, lymph nodes, heart and kidneys, characterized by pleomorphic lymphoid cells that were immunohistochemically positive for CD20. The presence of bovine leukemia virus (BLV) at >200,000 copies per 100,000 cells by quantitative RT-PCR was considered to be due to random integration of the provirus into the neoplastic cells´ genomes. Inverse PCR identified the presence of one, two, two and three different malignant clones in the heart, spleen, mesenteric node and blood, respectively. Because BLV can rapidly induce lymphoma and a high proviral load facilitates B-cell carcinogenesis, multiclonal tumor development was suspected in the present case.

Indexed as

Cattle DiseasesEnzootic Bovine LeukosisLeukemia Virus, BovineLymphoma, B-CellAnimalsCattlePolymerase Chain ReactionProvirusesbovine leukemia viruscattleinverse polymerase chain reactionmulticlonalitypleomorphic lymphoma

Identifiers

PMID35908937
PMCPMC9523288
OpenAlexW4289081922

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.