Evidence map›Paper›PMID 35910636›Full record

ReviewFrontiers in microbiology2022

Mycobiota and C-Type Lectin Receptors in Cancers: Know thy Neighbors.

Lilong Zhang, Dongqi Chai, Chen Chen, Chunlei Li, Zhendong Qiu, Tianrui Kuang, Mungur Parveena, Keshuai Dong, Jia Yu, Wenhong Deng and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Microbiota in cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  4. Article
  5. Review
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  7. Review
  8. Review
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  12. Article
  13. Article
  14. The associated risk ofFrontiers in oncology · 2023
    Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lilong ZhangDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Dongqi ChaiDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Chen ChenDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Chunlei LiDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Zhendong QiuDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Tianrui KuangDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Mungur ParveenaDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Keshuai DongDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Jia YuDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Wenhong DengDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Weixing WangDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have demonstrated the importance of gut bacteria in the development of malignancy, while relatively little research has been done on gut mycobiota. As a part of the gut microbiome, the percentage of gut mycobiota is negligible compared to gut bacteria. However, the effect of gut fungi on human health and disease is significant. This review systematically summarizes the research progress on mycobiota, especially gut fungi, in patients with head and neck cancer (HNC), esophageal cancer (EC), gastric cancer (GC), colorectal cancer (CRC), hepatocellular carcinoma (HCC), pancreatic cancer, melanoma, breast cancer, and lung carcinoma-induced cachexia. Moreover, we also describe, for the first time in detail, the role of the fungal recognition receptors, C-type lectin receptors (CLRs) (Dectin-1, Dectin-2, Dectin-3, and Mincle) and their downstream effector caspase recruitment domain-containing protein 9 (CARD9), in tumors to provide a reference for further research on intestinal fungi in the diagnosis and treatment of malignant tumors.

Indexed as

cancerCARD9Dectin-1Dectin-2Dectin-3dysbiosisgut mycobiotaMincle

Identifiers

PMID35910636
PMCPMC9326027
OpenAlexW4285088095

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.