ArticleTheranostics2022
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
- DCLK1-dependent NF-κB activation mediates p-STAT3-induced osteoarthritis progression.Clinical and translational medicine · 2026Article
- DCLK1 regulates stemness and IL-6/STAT3-dependent metastatic niche formation in chemoresistant ovarian cancer.Journal of experimental & clinical cancer research : CR · 2026Article
- Doublecortin-like kinase 1 promotes fibroblast activation and fibrotic progression through Smad3 binding in idiopathic pulmonary fibrosis.Journal of biomedical science · 2026Article
- Multi-omics analysis reveals the role of the XRCC gene family in diagnosis, prognosis, and immunity in pan-cancer.Discover oncology · 2026Article
- Dysadherin/YAP axis fuels stem plasticity and immune escape in liver cancer.Signal transduction and targeted therapy · 2025Article
- Tumor necrosis factor promotes doublecortin-like kinase 1 expression and cellular reprogramming in intestinal epithelial cells leading to neoplastic transformation.Cell communication and signaling : CCS · 2025Article
- Protein Marker-Dependent Drug Discovery Targeting Breast Cancer Stem Cells.International journal of molecular sciences · 2025Review
- DCLK1 isoform (DCLK1-S) as a critical player in promoting inflammation, tissue remodeling, and EMT in mouse models of colitis.PLoS pathogens · 2025Article
- Highlighting the Role of DCLK1 in Tumor Invasion and Potential for Therapeutic Intervention.Journal of cancer immunology · 2025Article
- Biomimetic Nano-delivery of Small-Molecule Piceatannol Modulates Tumor Stemness and Suppresses Colorectal Cancer Metastasis via Hippo/YAP1/SOX9 Signaling.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- From Inflammation to Oncogenesis: Tracing Serum DCLK1 and miRNA Signatures in Chronic Liver Diseases.International journal of molecular sciences · 2024Article
- Colonic Tuft Cells: The Less-Recognized Therapeutic Targets in Inflammatory Bowel Disease and Colorectal Cancer.International journal of molecular sciences · 2024Review
- Crosstalk between colorectal CSCs and immune cells in tumorigenesis, and strategies for targeting colorectal CSCs.Experimental hematology & oncology · 2024Review
- Correlation Between DCAMKL-1 Protein Expression and K-ras Gene Mutation in Colorectal Cancer.Cancer management and research · 2024Article
- Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome.Molecular medicine (Cambridge, Mass.) · 2023Article
- Epigenetic Landscape and Therapeutic Implication of Gene Isoforms of Doublecortin-Like Kinase 1 for Cancer Stem Cells.International journal of molecular sciences · 2023Review
- X-ray cross-complementing family: the bridge linking DNA damage repair and cancer.Journal of translational medicine · 2023Review
- Expression of Stem Cell Markers in High-LET Space Radiation-Induced Intestinal Tumors inCancers · 2023Article
- Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses.EMBO molecular medicine · 2023Article
- Cell-Type-Specific Gene Regulatory Networks of Pro-Inflammatory and Pro-Resolving Lipid Mediator Biosynthesis in the Immune System.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Jee-Heun KimSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
So-Yeon ParkSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
So-El JeonSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Jang-Hyun ChoiSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Choong-Jae LeeSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Tae-Young JangSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Hyeon-Ji YunSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Yuno LeeKorea Chemical Bank, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Pilho KimTherapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
Sang Hee ChoDepartment of Hemato-Oncology, Chonnam National University Medical School, Gwangju, 61469, Republic of Korea.
Ji Shin LeeDepartment of Pathology, Chonnam National University Medical School, Gwangju, 61469, Republic of Korea.
Jeong-Seok NamSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Gwangju Institute of Science and Technology · KRBank of Korea · KRChonnam National University Hospital · KRInstitute for Basic Science · KR
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Colorectal NeoplasmsDoublecortin-Like KinasesAnimalsComplement C5Cyclooxygenase 2Epithelial-Mesenchymal TransitionHumansIntracellular Signaling Peptides and ProteinsKu AutoantigenMiceNeoplastic Stem CellsProtein Serine-Threonine KinasesTumor MicroenvironmentX-RaysComplement C5Cyclooxygenase 2DCLK1 protein, humanDoublecortin-Like KinasesIntracellular Signaling Peptides and ProteinsKu AutoantigenProtein Serine-Threonine KinasesXRCC5 protein, humanCancer stem cellsDoublecortin-like kinase 1Inflammatory tumor microenvironmentProstaglandin E2
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.