Evidence map›Paper›PMID 35912151›Full record

Trial reportComputational and mathematical methods in medicine2022

The Level of HbA1c Evaluates the Extent of Coronary Atherosclerosis Lesions and the Prognosis in Diabetes with Acute Coronary Syndrome.

Shaodong Xu, Birong Zhou, Bingfeng Zhou, Jianfa Zheng, Qinghe Xu, Bing Wang, Minmin Fu, Ying Meng

RetractedOpen access · hybridAbstract readRandomized Controlled TrialRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shaodong XuDepartment of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230031 Anhui, China.ORCID https://orcid.org/0000-0002-1309-8428
Birong ZhouDepartment of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230031 Anhui, China.ORCID https://orcid.org/0000-0003-2846-6024
Bingfeng ZhouDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0002-4613-9900
Jianfa ZhengDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0002-4132-0583
Qinghe XuDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0002-2197-8142
Bing WangDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0002-9529-0690
Minmin FuDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0002-7710-7290
Ying MengDepartment of Cardiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, 230001 Anhui, China.ORCID https://orcid.org/0000-0001-7902-4918
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The level of HbA1c can reflect the average level of blood glucose over 3 months, which is the gold standard indicator for monitoring blood glucose. The relationship between the level of HbA1c and the extent of coronary atherosclerosis lesions or the prognosis in diabetes with acute coronary syndrome (ACS) remains poorly understood. Aims: To explore whether the level of HbA1c can evaluate the extent of coronary atherosclerosis lesions or the prognosis in diabetes with acute coronary syndrome (ACS) using the SYNTAX score, the Global Registry of Acute Coronary Events (GRACE) score, left ventricular function (LVEF), left ventricular end-diastolic volume (LVEDV), and major adverse cardiac events (MACEs) in the hospital and 12 months after discharge. Methods: This study was a prospective, randomized, open-label, and parallel group study. Patients with diabetes with ACS were recruited into this study indiscriminately, and all the participants were divided into two groups according to the level of HbA1c: HbA1c level ≤ 7%group and HbA1c level > 7%group. The followings were used as the evaluation indicators: SYNTAX score, GRACE score, LVEF, LVEDV, and MACEs in hospital and 12 months after discharge. Results: A total of 233 patients with diabetes and ACS were enrolled and assigned to two groups according to their level of HbA1c: the HbA1c ≤ 7%group ( Conclusions: This study shows that HbA1c level was positively correlated with the extent of coronary atherosclerosis lesions and the prognosis in diabetes with ACS. The higher the HbA1c level is, the more severe the coronary atherosclerotic lesion and the worse the prognosis in diabetes with ACS are.

Indexed as

Acute Coronary SyndromeCoronary Artery DiseaseDiabetes MellitusBlood GlucoseGlycated HemoglobinHumansPrognosisProspective StudiesRisk AssessmentBlood GlucoseGlycated Hemoglobin

Identifiers

PMID35912151
PMCPMC9337927
OpenAlexW4286615225

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.