Evidence map›Paper›PMID 35912790›Full record

ReviewJournal of dental research2022

FaceBase: A Community-Driven Hub for Data-Intensive Research.

R E Schuler, A Bugacov, J G Hacia, T V Ho, J Iwata, L Pearlman, B D Samuels, C Williams, Z Zhao, C Kesselman and 1 more

Abstract readReview
In one paragraph

Review in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

R E SchulerViterbi School of Engineering, Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA.ORCID 0000-0002-8956-5707
A BugacovViterbi School of Engineering, Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA.
J G HaciaKeck School of Medicine, Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA.
T V HoOstrow School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA, USA.
J IwataSchool of Dentistry, Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0003-3975-6836
L PearlmanViterbi School of Engineering, Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA.ORCID 0000-0002-0749-4707
B D SamuelsOstrow School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA, USA.
C WilliamsViterbi School of Engineering, Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA.
Z ZhaoSchool of Biomedical Informatics, Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
C KesselmanViterbi School of Engineering, Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA.
Y ChaiOstrow School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA, USA.

Funding

USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration HubU01DE028729 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHAI, YANG, KESSELMAN, CARL · 2019 to 2023
$13.9M
Role of cellular metabolism in palate morphogenesisR01DE029818 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI, ZHAO, ZHONGMING · 2020 to 2024
$1.8M
Deep learning for decoding genetic regulation and cellular maps in craniofacial developmentR01DE030122 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI, ZHAO, ZHONGMING · 2021 to 2023
$1.7M
Identification of microRNAs associated with cleft lipR03DE026509 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2017 to 2018
$462k
Transcripts and Functions Targeted by Non-coding RNAs in Palate DevelopmentR03DE026208 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2016 to 2017
$462k
Molecular Regulatory Network in Frontonasal DevelopmentR03DE028340 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2019 to 2020
$309k
Deep learning methods to predict the function of genetic variants in orofacial cleftsR03DE027711 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHAO, ZHONGMING · 2018 to 2019
$308k
Transcriptional and Post-transcriptional Co-regulation in Lip DevelopmentR03DE027393 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI, ZHAO, ZHONGMING · 2018 to 2019
$308k
Mining Genomic Data in FaceBase for Cleft GenesR03DE028103 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHAO, ZHONGMING · 2018 to 2019
$308k
NIDCR NIH HHS R01 DE029818NIDCR NIH HHS R01 DE030122NIDCR NIH HHS R03 DE026208NIDCR NIH HHS R03 DE026509NIDCR NIH HHS R03 DE027393NIDCR NIH HHS R03 DE027711NIDCR NIH HHS R03 DE028103NIDCR NIH HHS R03 DE028340NIDCR NIH HHS U01 DE028729
6 · The paper itself

Abstract

The FaceBase Consortium, funded by the National Institute of Dental and Craniofacial Research of the National Institutes of Health, was established in 2009 with the recognition that dental and craniofacial research are increasingly data-intensive disciplines. Data sharing is critical for the validation and reproducibility of results as well as to enable reuse of data. In service of these goals, data ought to be FAIR: Findable, Accessible, Interoperable, and Reusable. The FaceBase data repository and educational resources exemplify the FAIR principles and support a broad user community including researchers in craniofacial development, molecular genetics, and genomics. FaceBase demonstrates that a model in which researchers "self-curate" their data can be successful and scalable. We present the results of the first 2.5 y of FaceBase's operations as an open community and summarize the data sets published during this period. We then describe a research highlight from work on the identification of regulatory networks and noncoding RNAs involved in cleft lip with/without cleft palate that both used and in turn contributed new findings to publicly available FaceBase resources. Collectively, FaceBase serves as a dynamic and continuously evolving resource to facilitate data-intensive research, enhance data reproducibility, and perform deep phenotyping across multiple species in dental and craniofacial research.

Indexed as

Cleft PalateGenomicsHumansNational Institutes of Health (U.S.)PublicationsReproducibility of ResultsUnited Statescraniofacial abnormalitiesdata curationdevelopmental biologygenomicsmolecular geneticsmorphogenesis

Identifiers

PMID35912790
PMCPMC9516628

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.