Evidence map›Paper›PMID 35913188›Full record

ArticlemSystems2022

Multilayered Networks of SalmoNet2 Enable Strain Comparisons of the Salmonella Genus on a Molecular Level.

Marton Olbei, Balazs Bohar, David Fazekas, Matthew Madgwick, Padhmanand Sudhakar, Isabelle Hautefort, Aline Métris, Jozsef Baranyi, Robert A Kingsley, Tamas Korcsmaros

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Panomics to decode virulence and fitness in Gram-negative bacteria.Frontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Marton OlbeiEarlham Institute, Norwich, United Kingdom.ORCID 0000-0002-4903-6237
Balazs BoharEarlham Institute, Norwich, United Kingdom.
David FazekasEarlham Institute, Norwich, United Kingdom.
Matthew MadgwickEarlham Institute, Norwich, United Kingdom.
Padhmanand SudhakarEarlham Institute, Norwich, United Kingdom.
Isabelle HautefortEarlham Institute, Norwich, United Kingdom.
Aline MétrisQuadram Institute Biosciences, Norwich, United Kingdom.
Jozsef BaranyiQuadram Institute Biosciences, Norwich, United Kingdom.
Robert A KingsleyQuadram Institute Biosciences, Norwich, United Kingdom.
Tamas KorcsmarosEarlham Institute, Norwich, United Kingdom.
Quadram Institute · GBEötvös Loránd University · HUEarlham Institute · GBUniversity of Debrecen · HUUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/CSP1720/1Biotechnology and Biological Sciences Research Council BB/M011216/1Biotechnology and Biological Sciences Research Council BB/R012490/1Biotechnology and Biological Sciences Research Council BB/R012504/1Biotechnology and Biological Sciences Research Council BB/S50743X/1Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10348Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10349Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10355Biotechnology and Biological Sciences Research Council BBS/E/T/000PR9817Biotechnology and Biological Sciences Research Council BBS/E/T/000PR9819
6 · The paper itself

Abstract

Serovars of the genus Salmonella primarily evolved as gastrointestinal pathogens in a wide range of hosts. Some serotypes later evolved further, adopting a more invasive lifestyle in a narrower host range associated with systemic infections. A system-level knowledge of these pathogens could identify the complex adaptations associated with the evolution of serovars with distinct pathogenicity, host range, and risk to human health. This promises to aid the design of interventions and serve as a knowledge base in the Salmonella research community. Here, we present SalmoNet2, a major update to SalmoNet1, the first multilayered interaction resource for Salmonella strains, containing protein-protein, transcriptional regulatory, and enzyme-enzyme interactions. The new version extends the number of Salmonella networks from 11 to 20. We now include a strain from the second species in the Salmonella genus, a strain from the Salmonella enterica subspecies

Indexed as

Salmonella entericaSalmonella InfectionsHost SpecificityHumansMetabolic Networks and PathwaysSalmonellaglobal regulatory networkshost adaptationnetwork resourceprotein-protein interactionsSalmonella

Identifiers

PMID35913188
PMCPMC9426430
OpenAlexW4289339160

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.