Evidence map›Paper›PMID 35915256›Full record

ArticleNature reviews. Endocrinology2022

Lactate as a major myokine and exerkine.

George A Brooks, Adam D Osmond, Jose A Arevalo, Casey C Curl, Justin J Duong, Michael A Horning, Diana D Moreno Santillan, Robert G Leija

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Nature reviews. Endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Dynamic Metabolic Changes Driven by Exercise Intensity in Acute Swimming.Medicine and science in sports and exercise · 2025
    Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Lactate in Anaphylaxis: 100 Years On.Sports medicine (Auckland, N.Z.) · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. The Role of Myokines in Liver Diseases.International journal of molecular sciences · 2025
    Review
  18. Review
  19. Article
  20. Glioma neuron symbiosis: a hypothesis.Frontiers in neuroscience · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

George A BrooksExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA. gbrooks@berkeley.edu.ORCID 0000-0002-1389-1629
Adam D OsmondExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Jose A ArevaloExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Casey C CurlExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Justin J DuongExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Michael A HorningExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Diana D Moreno SantillanExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.
Robert G LeijaExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA, USA.

Funding

Aging Mitochondrial Fragmentation and Metabolic InflexibilityR01AG059715 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BROOKS, GEORGE AUSTIN · 2018 to 2022
$3.0M
NIA NIH HHS R01 AG059715
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lactic AcidMuscle Fibers, SkeletalHumansMuscle, SkeletalLactic Acid

Identifiers

PMID35915256

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.