ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2023
The combined effect of air and transportation noise pollution on atherosclerotic inflammation and risk of cardiovascular disease events.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Exposure-response relationship between transportation noise and cardiovascular disease outcomes: a systematic review and meta-regression analysis.Journal of exposure science & environmental epidemiology · 2026Pooled it
- The environmental exposome in heart failure risk and progression.Nature reviews. Cardiology · 2026Review
- Air, Noise, and Light Pollution and Thromboembolic Cardiovascular Complications: A TH Scientific Statement.Thrombosis and haemostasis · 2026Article
- Hormonal Contraceptive Use, Stress Disorders, and Cardiovascular and Thrombotic Risk in Women.JAMA network open · 2026Article
- Association between noise pollution perception and prevalence of cardiovascular disease in a Chinese adult population: a cross-sectional study based on the CGSS 2021 cardiovascular disease dataset.Frontiers in public health · 2026Article
- Living close to risk: disentangling associations of the residential exposome and socioeconomic disparities with coronary artery disease.European journal of preventive cardiology · 2025Article
- Imaging Findings Associated With Socioenvironmental Exposures Inform Mechanisms of Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Long-term nighttime aircraft noise exposure and risk of hypertension in a prospective cohort of female nurses.International journal of hygiene and environmental health · 2025Article
- Association between long-term exposure to low ambient PMEnvironment international · 2024Article
- Understanding the Cardiovascular and Metabolic Health Effects of Air Pollution in the Context of Cumulative Exposomic Impacts.Circulation research · 2024Review
- Effects of lifestyle factors on leukocytes in cardiovascular health and disease.Nature reviews. Cardiology · 2024Review
- Exposome in ischaemic heart disease: beyond traditional risk factors.European heart journal · 2024Review
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.GeroScience · 2023Review
- Associations between long-term aircraft noise exposure, cardiovascular disease, and mortality in US cohorts of female nurses.Environmental epidemiology (Philadelphia, Pa.) · 2023Article
- Association Between Historical Neighborhood Redlining and Cardiovascular Outcomes Among US Veterans With Atherosclerotic Cardiovascular Diseases.JAMA network open · 2023Article
- Impact of the exposome on cardiovascular disease.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAir pollution and noise exposures individually associate with major adverse cardiovascular events (MACE) via a mechanism involving arterial inflammation (ArtI); however, their combined impact on ArtI and MACE remains unknown. We tested whether dual (vs. one or neither) exposure associates with greater ArtI and MACE risk and whether MACE risk is mediated via ArtI.
methodsIndividuals (N = 474) without active cancer or known cardiovascular disease with clinical
resultsAt baseline, 46%, 46%, and 8% were exposed to high levels of neither, one, or both pollutants; 39 experienced MACE over a median 4.1 years. Exposure to an increasing number of pollutants associated with higher ArtI (standardized β [95% CI: .195 [.052, .339], P = .008) and MACE (HR [95% CI]: 2.897 [1.818-4.615], P < .001). In path analysis, ArtI partially mediated the relationship between pollutant exposures and MACE (P < .05).
conclusionAir pollution and transportation noise exposures contribute incrementally to ArtI and MACE. The mechanism linking dual exposure to MACE involves ArtI.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.