Evidence map›Paper›PMID 35916388›Full record

ArticleAmerican journal of epidemiology2022

A Bespoke Instrumental Variable Approach to Correction for Exposure Measurement Error.

David B Richardson, Alexander P Keil, Jessie K Edwards, Stephen R Cole, Eric J Tchetgen Tchetgen

Open access · greenAbstract read
In one paragraph

Article in American journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

David B Richardson
Alexander P Keil
Jessie K Edwards
Stephen R Cole
Eric J Tchetgen Tchetgen
University of California, Irvine · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Novel Designs and Methods to Remove Hidden Confounding Bias in Health SciencesR01AG065276 · NIA · UNIVERSITY OF PENNSYLVANIA · PI TCHETGEN TCHETGEN, ERIC JOEL · 2020 to 2024
$2.4M
Occupational Exposure to Ionizing Radiation: Models for Policy MakingR01OH011409 · OH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RICHARDSON, DAVID B · 2017 to 2021
$814k
NCI NIH HHS P30 CA062203NIA NIH HHS R01 AG065276NIOSH CDC HHS R01 OH011409
6 · The paper itself

Abstract

A covariate-adjusted estimate of an exposure-outcome association may be biased if the exposure variable suffers measurement error. We propose an approach to correct for exposure measurement error in a covariate-adjusted estimate of the association between a continuous exposure variable and outcome of interest. Our proposed approach requires data for a reference population in which the exposure was a priori set to some known level (e.g., 0, and is therefore unexposed); however, our approach does not require an exposure validation study or replicate measures of exposure, which are typically needed when addressing bias due to exposure measurement error. A key condition for this method, which we refer to as "partial population exchangeability," requires that the association between a measured covariate and outcome in the reference population equals the association between that covariate and outcome in the target population in the absence of exposure. We illustrate the approach using simulations and an example.

Indexed as

Research DesignBiasHumansbiascohort studiesepidemiologic methodsregression analysis

Identifiers

PMID35916388
PMCPMC10144664
OpenAlexW4289523822

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.