ArticleThe Journal of clinical endocrinology and metabolism2022
Diabetic Ketoacidosis in Pregnancy: Clinical Risk Factors, Presentation, and Outcomes.
Article in The Journal of clinical endocrinology and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Automated insulin delivery in pregnant women with type 1 diabetes mellitus: a systematic review and meta-analysis.Acta diabetologica · 2025Pooled it
- Euglycemic Diabetic Ketoacidosis Presenting With Intraoperative Cardiac Arrest in Late Pregnancy.Cureus · 2026Article
- Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report.The American journal of case reports · 2026Article
- 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Perioperative management of emergency cesarean delivery in a pregnant woman with uncorrected diabetic ketoacidosis: a case report.JA clinical reports · 2025Article
- Maternal and Perinatal Outcomes in Pregnancies With Type 1 Diabetes and Controls During a 15-Year Period (2006-2020).Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Stress-Induced Transient Diabetic Ketoacidosis (DKA) in Pregnancy Without Pre-existing Diabetes.Cureus · 2025Article
- Managing diabetic ketoacidosis in special conditions: Difficulties and dilemmas.World journal of diabetes · 2025Review
- Medical Nutrition Therapy for Women with Gestational Diabetes: Current Practice and Future Perspectives.Nutrients · 2025Review
- Diabetic Ketoacidosis in Pregnancy: A Systematic Review of the Reported Cases.Clinical medicine insights. Endocrinology and diabetes · 2025Review
- 6. Glycemic Goals and Hypoglycemia: Standards of Care in Diabetes-2025.Diabetes care · 2025Review
- Article
- Diagnosis and Treatment of Hyperglycemia in Pregnancy: Type 2 Diabetes Mellitus and Gestational Diabetes.Endocrinology and metabolism clinics of North America · 2024Review
- Hyperglycemic Crises in Adults With Diabetes: A Consensus Report.Diabetes care · 2024Review
- Hyperglycaemic crises in adults with diabetes: a consensus report.Diabetologia · 2024Article
- Causal pathways in preeclampsia: a Mendelian randomization study in European populations.Frontiers in endocrinology · 2024Article
- Diabetes Mellitus Type 1 Presenting in the Setting of Diabetic Ketoacidosis and Acute SARS-CoV-2 Infection in Pregnancy.AACE clinical case reports · 2023Article
- Pregnancy and diabetic ketoacidosis: fetal jeopardy and windows of opportunity.Frontiers in clinical diabetes and healthcare · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
contextDiabetic ketoacidosis (DKA) in pregnancy is an obstetric emergency with risk of maternofetal death.
objectiveThis work aimed to evaluate DKA events in pregnant women admitted to our inpatient obstetric service, and to examine associated clinical risk factors, presentation, and pregnancy outcomes.
methodsA retrospective cohort study was conducted at the Mayo Clinic, Rochester, Minnesota, USA, and included women aged 17 to 45 years who were treated for DKA during pregnancy between January 1, 2004 and December 31, 2021. Main outcome measures included maternal and fetal death along with a broad spectrum of maternal and fetal pregnancy outcomes.
resultsA total of 71 DKA events were identified in 58 pregnancies among 51 women, 48 (82.8%) of whom had type 1 diabetes. There were no maternal deaths, but fetal demise occurred in 10 (17.2%) pregnancies (6 miscarriages and 4 stillbirths). Maternal social stressors were frequently present (n = 30, 51.0%), and glycemic control was suboptimal (median first trimester glycated hemoglobin A1c = 9.0%). Preeclampsia was diagnosed in 17 (29.3%) pregnancies. Infants born to women with DKA were large for gestational age (n = 16, 33.3%), suffered from neonatal hypoglycemia (n = 29, 60.4%) and required intensive care unit admission (n = 25, 52.1%).
conclusionDKA is associated with a high rate of maternofetal morbidity and fetal loss. Prenatal education strategies for women with diabetes mellitus should include a strong focus on DKA prevention, and clinicians and patients should have a high index of suspicion for DKA in all pregnant women who present with symptoms that could be attributed to this condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.