ArticleScientific reports2022
Association between central obesity and incident diabetes mellitus among Japanese: a retrospective cohort study using propensity score matching.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 29 citations in OpenAlex.
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- A correlation analysis between TyG-derived indices and diabetes mellitus: based on the NHANES database.Endocrine journal · 2026Article
- The relationship between plasma sphingosine-1-phosphate, plasma apolipoprotein M, obesity, and the risk of incident type 2 diabetes: a prospective cohort study.International journal of obesity (2005) · 2025Article
- Associations between dynapenic abdominal obesity and diabetes in middle aged and older Chinese.Scientific reports · 2025Article
- Causal relationship between body mass index and insulin resistance: Linear and nonlinear Mendelian randomization study in a Japanese population.Journal of diabetes investigation · 2025Article
- Triglyceride-glycated hemoglobin index as a superior predictor of type 2 diabetes risk in a large-scale retrospective cohort study.Scientific reports · 2025Article
- Obesity in Italy: An Empirical Analysis of Healthcare Consumption, Quality of Life and Comorbidities.Medicina (Kaunas, Lithuania) · 2025Article
- Association of estimated small dense low-density lipoprotein cholesterol with diabetes mellitus: a large-scale multicenter retrospective cohort study.BMC endocrine disorders · 2025Article
- Classification and identification of risk factors for type 2 diabetes.World journal of diabetes · 2025Review
- Body Mass Index and the Risk of Hypertension-Diabetes Comorbidity in Elderly Population: A Prospective Cohort in China.Global heart · 2025Observational
- Anthropometric Indices and Diabetes Disease: Based on the Rafsanjan Cohort Study.International journal of preventive medicine · 2025Article
- Non-linear relationship between lipid accumulation products and risk of diabetes in Japanese adults.Scientific reports · 2024Article
- National trends in type 2 diabetes mellitus stratified by central adiposity using waist-to-height ratio in South Korea, 2005-2022.Scientific reports · 2024Article
- Non-linear relationship between relative fat mass and diabetes risk in Japanese adults: a retrospective cohort study.Scientific reports · 2024Article
- Impact of adiposity indices changes across the lifespan on risk of diabetes in women: trajectory modeling approach.BMC public health · 2024Article
- Association between excessive alcohol consumption and incident diabetes mellitus among Japanese based on propensity score matching.Scientific reports · 2024Article
- Trends of HbA1c and BMI in People with Type 2 Diabetes: A Japanese Claims-Based Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Article
- The interaction between general or abdominal obesity and hypertension on the risk of type 2 diabetes mellitus: a cross-sectional analysis in Iranian adults from the RaNCD cohort study.BMC public health · 2024Article
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6 authors at 4 institutions in 1 country.
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Abstract
Previous evidence revealed that central obesity played a vital role in the development of diabetes mellitus (DM). However, because of imbalanced confounding variables, some studies have not wholly established the association between central obesity and diabetes. Propensity score matching (PSM) analysis can minimize the impact of potential confounding variables. Therefore, the aim of the present study was to explore the relationship between central obesity and diabetes in the Japanese population by using PSM analysis. This retrospective cohort study included 15,453 Japanese adults who were free of diabetes at baseline between 2004 and 2015, which provided all medical records for individuals participating in the physical exam. Central obesity at baseline was an independent variable, and incident diabetes during follow-up was an outcome variable. Using a 1:1 PSM analysis, the present retrospective cohort study included 1639 adults with and without central obesity. Additionally, we employed a doubly robust estimation method to identify the association between central obesity and diabetes. Subjects with central obesity were 92% more likely to develop DM (HR = 1.65, 95%CI 1.12, 2.41). After adjusting for covariates, subjects with central obesity had a 72% increased risk of developing DM compared with subjects with non-central obesity in the PSM cohort (HR = 1.72, 95% CI 1.16, 2.56). Central obesity individuals had a 91% higher risk of DM than non-central obesity individuals, after adjustment for propensity score (HR = 1.91, 95% CI 1.29, 2.81). In sensitivity analysis, the central obesity group had a 44% (HR = 1.44, 95% CI 1.09, 1.90) and 59% (HR = 1.59, 95% CI1.35, 1.88) higher risk of DM than the non-central obesity group in the original and weighted cohorts after adjusting for confounding variables, respectively. Central obesity was independently associated with an increased risk of developing diabetes. After adjustment for confounding covariates, central obesity participants had a 72% higher risk of development of diabetes than non-central obesity individuals in the PSM cohort.
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