Evidence map›Paper›PMID 35928164›Full record

ArticleFrontiers in microbiology2022

Homology-based reconstruction of regulatory networks for bacterial and archaeal genomes.

Luis Romero, Sebastian Contreras-Riquelme, Manuel Lira, Alberto J M Martin, Ernesto Perez-Rueda

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. ENcyclopedia of TRAnscription Factors in Bacteria and Archaea genomes (ENTRAF) version 2.0.Database : the journal of biological databases and curation · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Luis RomeroLicenciatura en Ciencias Genomicas, Universidad Nacional Autonoma de Mexico, Cuernavaca, Mexico.
Sebastian Contreras-RiquelmeLaboratorio de Biología de Redes, Centro de Genómica y Bioinformática, Facultad Ciencias, Ingeniería y Tecnología, Universidad Mayor, Santiago, Chile.
Manuel LiraCómputo Académico, Facultad de Ciencias - UMDI-Sisal, Sede Parque Científico y Tecnológico de Yucatán, Universidad Nacional Autónoma de México, Mérida, Mexico.
Alberto J M MartinLaboratorio de Biología de Redes, Centro de Genómica y Bioinformática, Facultad Ciencias, Ingeniería y Tecnología, Universidad Mayor, Santiago, Chile.
Ernesto Perez-RuedaInstituto de Investigaciones en Matemáticas Aplicadas y en Sistemas, Universidad Nacional Autónoma de México, Unidad Académica Yucatán, Mérida, Mexico.
Universidad Nacional Autónoma de México · MXUniversidad Mayor · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene regulation is a key process for all microorganisms, as it allows them to adapt to different environmental stimuli. However, despite the relevance of gene expression control, for only a handful of organisms is there related information about genome regulation. In this work, we inferred the gene regulatory networks (GRNs) of bacterial and archaeal genomes by comparisons with six organisms with well-known regulatory interactions. The references we used are:

Indexed as

genomicsorthologyregulatory modulesregulatory networkstranscription units

Identifiers

PMID35928164
PMCPMC9344073
OpenAlexW4285798519

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.