Evidence map›Paper›PMID 35928897›Full record

ArticleFrontiers in endocrinology2022

Short-time intensive insulin therapy upregulates 3 beta- and 17 beta-hydroxysteroid dehydrogenase levels in men with newly diagnosed T2DM.

Yun Hu, Ying Wang, Ting-Ting Cai, Lu Liu, Dong-Mei Li, Jian-Hua Ma, Bo Ding

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yun HuDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Ying WangDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Ting-Ting CaiDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Lu LiuDepartment of Endocrinology, Chunjiang People's Hospital, Changzhou, China.
Dong-Mei LiDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Jian-Hua MaDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Bo DingDepartment of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNQujiang People's Hospital · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Our previous study has found that short-term intensive insulin therapy in patients with newly diagnosed type 2 diabetes mellitus (T2DM) increased serum testosterone levels, but the underlying mechanisms remain unclear. Design and methods: In this self-controlled study, 43 men with newly diagnosed drug naïve T2DM, aged 18-60 years, with HbA Results: Testosterone increased from 13.0 (11.3, 14.6) nmol/L to 15.7 (13.9, 17.5) nmol/L after intensive insulin therapy ( Conclusions: Blood glucose normalization

Indexed as

Diabetes Mellitus, Type 2Insulin17-Hydroxysteroid DehydrogenasesBlood GlucoseDehydroepiandrosteroneHumansMaleTestosterone17-Hydroxysteroid Dehydrogenases3 (or 17)-beta-hydroxysteroid dehydrogenaseBlood GlucoseDehydroepiandrosteroneInsulinTestosteronebeta-hydroxysteroid dehydrogenasedehydroepiandrosterone sulfatediabetes mellitusinsulintestosterone

Identifiers

PMID35928897
PMCPMC9344891
OpenAlexW4285794914

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.