ArticleJournal of the American Heart Association2022
Causal Association of Cardiovascular Risk Factors and Lifestyle Behaviors With Peripheral Artery Disease: A Mendelian Randomization Approach.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Alcohol Exposure and Disease Associations: A Mendelian Randomization and Meta-Analysis on Weekly Consumption and Problematic Drinking.Nutrients · 2024Pooled it
- Article
- Evidence-based sleep promotion in acute care from the perspective of nursing staff: a cross-sectional study.BMC nursing · 2026Article
- Correlations Between Coffee Intake, Glycemic Control, Cardiovascular Risk, and Sleep in Type 2 Diabetes and Hypertension: A 12-Month Observational Study.Biomedicines · 2025Article
- Identifying potential drug targets for tourette syndrome: a Mendelian randomization study based on druggable genes.Italian journal of pediatrics · 2025Article
- Modifiable and Non-Modifiable Risk Factors and Vascular Damage Progression in Type 2 Diabetes: A Primary Care Analysis.Journal of clinical medicine · 2025Article
- Interaction and combined effect of triglyceride-glucose index and hypertension on type 2 diabetes individuals' peripheral arterial disease risk.Acta diabetologica · 2025Article
- Letter to the Editor on "The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study".Sexual medicine · 2025Article
- Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: a Mendelian randomization study.Scientific reports · 2025Article
- Observational
- Analysis of risk factors and predictive value of a nomogram for peripheral arterial disease in patients with type 2 diabetes.Frontiers in endocrinology · 2025Article
- Causal relationship between serum uric acid and cardiovascular disease: A Mendelian randomization study.International journal of cardiology. Heart & vasculature · 2024Article
- Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study.Frontiers in nutrition · 2024Article
- Article
- Mendelian randomization for cardiovascular diseases: principles and applications.European heart journal · 2023Review
- The causal association between smoking initiation, alcohol and coffee consumption, and women's reproductive health: A two-sample Mendelian randomization analysis.Frontiers in genetics · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background We investigated the causal associations between the genetic liability to cardiovascular and lifestyle risk factors and peripheral artery disease (PAD), using a Mendelian randomization approach. Methods and Results We performed a 2-sample inverse-variance weighted Mendelian randomization analysis, multiple sensitivity analyses to assess pleiotropy and multivariate Mendelian randomization analyses to assess mediating/confounding factors. European-ancestry genomic summary data (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.