Evidence map›Paper›PMID 35936471›Full record

ArticleACS omega2022

Graphene Quantum-Dot-Based Nanophotonic Approach for Targeted Detection of Long Noncoding RNAs in Circulation.

Ruchita Shandilya, Arpit Bhargava, Pooja Ratre, Roshani Kumari, Rajnarayan Tiwari, Prachi Chauhan, Pradyumna Kumar Mishra

Abstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Quantum Dots-Based Protocols for the Detection of RNAs.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruchita ShandilyaDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Arpit BhargavaDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Pooja RatreDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Roshani KumariDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Rajnarayan TiwariDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Prachi ChauhanDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Pradyumna Kumar MishraDepartment of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.ORCID https://orcid.org/0000-0002-0795-2819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent progress in the field of nanophotonics has opened up novel avenues for developing nanomaterial-based biosensing systems, which can detect various disease-specific biomarkers, including long noncoding RNAs (lncRNAs) known to circulate in biological fluids. Herein, we designed and developed a nanophotonic approach for rapid and specific capture of lncRNAs using oligonucleotide-conjugated graphene quantum-dot-nanoconjugates. The method offers accurate identification of the target lncRNAs with high selectivity, despite the presence of other molecules in the given sample. The observations also pointed toward the high feasibility and simplicity of the method in the selective determination of lncRNAs. Overall, the approach has the potential of assessing lncRNA expression as a function of disease initiation and progression.

Identifiers

PMID35936471
PMCPMC9352251

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.