Evidence mapPaperPMID 35936770Full record

ArticleFrontiers in aging neuroscience2022

Exercise Effects on Cognition in Older African Americans: A Pilot Randomized Trial.

Kathryn L Gwizdala, Robert Brouillete, Robbie Beyl, William Johnson, Callie Hebert, Leah Carter, Melissa Harris, Robert L Newton, Owen T Carmichael

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03474302 (Program for African American Cognition & Exercise), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03474302 nacompletednot on this map

Program for African American Cognition & Exercise

TypeinterventionalSponsorPennington Biomedical Research CenterRan2018 to 2019Enrolled56ConditionsAgingArmsPhysical Activity, Successful Aging
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kathryn L GwizdalaPennington Biomedical Research Center, Baton Rouge, LA, United States.
Robert BrouilletePennington Biomedical Research Center, Baton Rouge, LA, United States.
Robbie BeylPennington Biomedical Research Center, Baton Rouge, LA, United States.
William JohnsonPennington Biomedical Research Center, Baton Rouge, LA, United States.
Callie HebertPennington Biomedical Research Center, Baton Rouge, LA, United States.
Leah CarterPennington Biomedical Research Center, Baton Rouge, LA, United States.
Melissa HarrisPennington Biomedical Research Center, Baton Rouge, LA, United States.
Robert L NewtonPennington Biomedical Research Center, Baton Rouge, LA, United States.
Owen T CarmichaelPennington Biomedical Research Center, Baton Rouge, LA, United States.
Pennington Biomedical Research Center · US

Funding

Louisiana Clinical and Translational Science CenterU54GM104940 · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2025 to 2025
$3.9M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Introduction: Regular physical activity lowers risk for cognitive decline and neurodegenerative disorders. Older African Americans (AAs) have been underrepresented in trials that increased physical activity to improve cognitive outcomes. Methods: 56 sedentary, older, cognitively healthy AAs (avg. 69.2 ± 3.4 yrs. old) were randomized in 1:1 ratio into either a 12-week successful aging group (SAG) or a 12-week physical activity group (PAG). Participants in SAG attended weekly 60-min educational sessions in which healthy aging topics were discussed. Participants in PAG attended supervised physical activity sessions twice per week at local YMCAs (90-120 min/week) and were prescribed 2-3 days per week of home-based activity. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) assessed cognitive function. ANCOVA models compared mean 12-week change in global cognition and subdomain scores between groups with secondary analyses for sex differences. Effect sizes for RBANS were calculated. Results: The RBANS global cognition score (SAG Est. 5.6 ± 1.8, effect size = 0.37, Discussion: A 12-week physical activity intervention (PAG) did not improve cognitive functioning among older AAs but a comparator healthy aging education program did. Inadequate physical activity dosage or duration, SAG members acting on health-related information from educational sessions, and/or social stimulation within the SAG may have contributed to these results. Future studies should combine socially engaging activities with vigorous physical activity for cognitive enhancement among cognitively healthy older African Americans. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT03474302.

Indexed as

African AmericanAlzheimer’s diseasecognitive functiondementia preventionphysical activity

Identifiers

PMID35936770
PMCPMC9354972
OpenAlexW4286487961

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.