Evidence map›Paper›PMID 35936890›Full record

ReviewFrontiers in physiology2022

Sirtuins and cognition: implications for learning and memory in neurological disorders.

Eric Fagerli, Iris Escobar, Fernando J Ferrier, Charles W Jackson, Efrain J Perez-Lao, Miguel A Perez-Pinzon

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Sirtuins, redox, and metabolic pathways in the brain of female PCOS mice.Journal of assisted reproduction and genetics · 2025
    Article
  5. Sirtuins Contribute to the Migraine-Stroke Connection.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Exercise to Mitigate Cerebrovascular Aging: A Geroscience Perspective.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eric FagerliDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Iris EscobarDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Fernando J FerrierDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Charles W JacksonDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Efrain J Perez-LaoDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Miguel A Perez-PinzonDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States.
University of Miami · US

Funding

ISCHEMIC PRECONDITIONING: MECHANISMS OF NEUROPROTECTIONR01NS034773 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MIGUEL A PEREZ-PINZON · 2003 to 2026
$6.7M
ISCHEMIC PRECONDITIONING: MECHANISMS OF NEUROPROTECTIONRF1NS034773 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PEREZ-PINZON, MIGUEL A · 2022 to 2022
$1.7M
ISCHEMIC PRECONDITIONING--MECHANISMS OF NEUROPROTECTIONR29NS034773 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PEREZ-PINZON, MIGUEL A · 1997 to 2001
$267k
NINDS NIH HHS R01 NS034773NINDS NIH HHS R29 NS034773NINDS NIH HHS RF1 NS034773
6 · The paper itself

Abstract

Sirtuins are an evolutionarily conserved family of regulatory proteins that function in an NAD

Indexed as

Alzheimer’s diseasecognitionepigeneticsischemiamemoryoxidative stresssirtuinssynaptic plasticity

Identifiers

PMID35936890
PMCPMC9355297
OpenAlexW4286560194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.