Evidence map›Paper›PMID 35938865›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Mucins MUC5AC and MUC5B in the Airways: MUCing around Together.

Mehmet Kesimer

Open access · hybridAbstract readEditorialComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  7. A translational view of airway epithelial dysfunction in COPD.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Mehmet KesimerMarsico Lung Institute and Department of Pathology and Laboratory Medicine The University of North Carolina at Chapel Hill Chapel Hill, North Carolina.ORCID 0000-0003-3867-1873
University of North Carolina at Chapel Hill · US

Funding

SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
The effect of Inhaled Nicotine on Pulmonary SurfacesR01HL135642 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESIMER, MEHMET, TARRAN, ROBERT · 2017 to 2021
$2.9M
The role of mucin-protein interactions in the innate defense of the lungR01HL103940 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESIMER, MEHMET · 2010 to 2014
$1.8M
Airway mucus/mucin composition and proteome in COPD: A SPIROMICS ancillary studyR01HL110906 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESIMER, MEHMET · 2011 to 2014
$1.4M
NHLBI NIH HHS 5U01HL137880NHLBI NIH HHS R01 HL103940NHLBI NIH HHS R01HL103940NHLBI NIH HHS R01 HL110906NHLBI NIH HHS R01HL110906NHLBI NIH HHS R01 HL135642NHLBI NIH HHS R01HL135642NHLBI NIH HHS U01 HL137880
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mucin 5ACMucin-5BHumansSecretory VesiclesMUC5AC protein, humanMUC5B protein, humanMucin 5ACMucin-5B

Identifiers

PMID35938865
PMCPMC9704829
OpenAlexW4290643109

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.