Evidence map›Paper›PMID 35940589›Full record

ReviewACS infectious diseases2022

Two Years into the COVID-19 Pandemic: Lessons Learned.

Severino Jefferson Ribeiro da Silva, Jessica Catarine Frutuoso do Nascimento, Renata Pessôa Germano Mendes, Klarissa Miranda Guarines, Caroline Targino Alves da Silva, Poliana Gomes da Silva, Jurandy Júnior Ferraz de Magalhães, Justin R J Vigar, Abelardo Silva-Júnior, Alain Kohl and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in ACS infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Reverse Risk Register Approach to Understanding Systemic Factors in Risk Analysis and Management Case Studies.Risk analysis : an official publication of the Society for Risk Analysis · 2026
    Article
  4. Article
  5. Rapid On-Site Detection ofPlants (Basel, Switzerland) · 2026
    Article
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  15. Effectiveness of SARS-CoV-2 testing strategies.The Cochrane database of systematic reviews · 2025
    Article
  16. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Severino Jefferson Ribeiro da SilvaLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Jessica Catarine Frutuoso do NascimentoLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Renata Pessôa Germano MendesLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Klarissa Miranda GuarinesLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Caroline Targino Alves da SilvaLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Poliana Gomes da SilvaLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Jurandy Júnior Ferraz de MagalhãesLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.
Justin R J VigarDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
Abelardo Silva-JúniorInstitute of Biological and Health Sciences, Federal University of Alagoas (UFAL), 57072-900 Maceió, Alagoas, Brazil.
Alain KohlMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, United Kingdom.
Keith PardeeDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.ORCID 0000-0002-3812-8013
Lindomar PenaLaboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), 50670-420 Recife, Pernambuco, Brazil.ORCID 0000-0003-1134-5699
Fundação Oswaldo Cruz · BRUniversity of Toronto · CAMRC University of Glasgow Centre for Virus Research · GBUniversidade Federal de Alagoas · BR

Funding

CIHR 950-231075Medical Research Council MC_PC_19026Medical Research Council MC_UU_12014/8
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan, China, causing a respiratory disease called coronavirus disease 2019 (COVID-19), which has massively impacted global public health and caused widespread disruption to daily life. The crisis caused by COVID-19 has mobilized scientists and public health authorities across the world to rapidly improve our knowledge about this devastating disease, shedding light on its management and control, and spawned the development of new countermeasures. Here we provide an overview of the state of the art of knowledge gained in the last 2 years about the virus and COVID-19, including its origin and natural reservoir hosts, viral etiology, epidemiology, modes of transmission, clinical manifestations, pathophysiology, diagnosis, treatment, prevention, emerging variants, and vaccines, highlighting important differences from previously known highly pathogenic coronaviruses. We also discuss selected key discoveries from each topic and underline the gaps of knowledge for future investigations.

Indexed as

COVID-19PandemicsChinaHumansPublic HealthSARS-CoV-2clinical featuresdiagnosispathophysiologypreventionreservoir hostsSARS-CoV-2transmissiontreatmentvaccinesvariants

Identifiers

PMID35940589
PMCPMC9380879
OpenAlexW4290695246

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.