Evidence map›Paper›PMID 35948664›Full record

ReviewJournal of exposure science & environmental epidemiology2023

Biomonitoring of inorganic arsenic species in pregnancy.

Jillian Ashley-Martin, Mandy Fisher, Patrick Belanger, Ciprian Mihai Cirtiu, Tye E Arbuckle

Abstract readReview
In one paragraph

Review in Journal of exposure science & environmental epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Persistent effects of early-life arsenic exposure inEnvironmental science. Processes & impacts · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Interplay Between Vitamin D Levels and Heavy Metals Exposure in Pregnancy and Childbirth: A Systematic Review.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jillian Ashley-MartinEnvironmental Health, Science and Research Bureau, Health Canada, Ottawa, ON, Canada. jillian.ashley-martin@hc-sc.gc.ca.ORCID 0000-0001-9958-7531
Mandy FisherEnvironmental Health, Science and Research Bureau, Health Canada, Ottawa, ON, Canada.
Patrick BelangerINSPQ, Centre de toxicologie du Québec, Direction de la santé environnementale, au travail et de la toxicology, Quebec, QC, Canada.
Ciprian Mihai CirtiuINSPQ, Centre de toxicologie du Québec, Direction de la santé environnementale, au travail et de la toxicology, Quebec, QC, Canada.
Tye E ArbuckleEnvironmental Health, Science and Research Bureau, Health Canada, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure assessment of inorganic arsenic is challenging due to the existence of multiple species, complexity of arsenic metabolism, and variety of exposure sources. Exposure assessment of arsenic during pregnancy is further complicated by the physiological changes that occur to support fetal growth. Given the well-established toxicity of inorganic arsenic at high concentrations, continued research into the potential health effects of low-level exposure on maternal and fetal health is necessary. Our objectives were to review the value of and challenges inherent in measuring inorganic arsenic species in pregnancy and highlight related research priorities. We discussed how the physiological changes of pregnancy influence arsenic metabolism and necessitate the need for pregnancy-specific data. We reviewed the biomonitoring challenges according to common and novel biological matrices and discussed how each matrix differs according to half-life, bioavailability, availability of laboratory methods, and interpretation within pregnancy. Exposure assessment in both established and novel matrices that accounts for the physiological changes of pregnancy and complexity of speciation is a research priority. Standardization of laboratory method for novel matrices will help address these data gaps. Research is particularly lacking in contemporary populations of pregnant women without naturally elevated arsenic drinking water concentrations (i.e. <10 µg/l).

Indexed as

ArsenicArsenicalsDrinking WaterBiological MonitoringFemaleFetusHumansPregnancyArsenicArsenicalsDrinking WaterArsenicBiomonitoringCohort studiesPregnancySpeciated arsenic

Identifiers

PMID35948664
PMCPMC10733137

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.